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MetabolomicsResearch on the quality markers of antioxidant activity of Kai-Xin-San based on spectrum-effect relationship
Kai-Xin-San (KXS) is one of the classic famous traditional Chinese medicine prescriptions for amnesia, which has been applied for thousands of years. Modern pharmacological research has found that KXS has significant therapeutic efficacy on nervous system diseases, which is related to its antioxidan...
2023-12-21 | MTBLS8806 | MetaboLights
MetabolomicsA Combined Proteomic and Metabolomic Strategy for Allergens Characterization in Natural and Fermented Brassica napus Bee Pollen

Bee pollen is consumed for its nutritional and pharmacological benefits, but it also contains hazardous allergens which has not been identified. Here, we identified 2 potential allergens, glutaredoxin and oleosin-B2, in Brassica napus (B. napus) bee pollen using mass spectrometr...

2022-03-23 | MTBLS3950 | MetaboLights
ProteomicsProteomics reveals the mechanism of Qingre Huo xue decoction in treating rheumatoid arthritis
Rheumatoid arthritis is an autoimmune disease characterized by chronic synovitis, which can lead to irreversible joint damage as well as cardiovascular and respiratory system damage. The Qingre Huoxue Decoction is a Chinese medicine compound that has been clinically proven to be effective in treatin...
ORGANISM(S): Homo Sapiens 
2024-07-23 | PXD054129 |
ProteomicsLysine 2-hyroxyisobutyrylome, acetylome and succinylome in prokaryotes
identification of lysine 2-hyroxyisobutyrylome, acetylome and succinylome in prokaryotes
ORGANISM(S): Proteus Mirabilis Atcc 29906 Escherichia Coli 
2019-04-04 | PXD013377 |
ProteomicsDNA-guided Photoactivatable Probe-based Chemical Proteomics Reveals the Reader Protein of mRNA Methylation
We report a DNA templated chemistry and photo-crosslinking based method to detect the readers of mRNA modification. By use of N6-methyladenosine (m6A), we illustrated that this method can be successfully utilized for labelling and enriching the readers of mRNA modification, as well as for the discov...
ORGANISM(S): Homo Sapiens 
2020-05-30 | PXD019480 |
ProteomicsSILAC experiments profiling of the proteome of WT and CobB KO E.coli
SILAC experiments profiling of the proteome of WT and CobB KO E.coli
ORGANISM(S): Escherichia Coli 
2021-12-11 | PXD030345 |
ProteomicsSILAC experiments profiling of the proteome of WT and YiaC KO E.coli
SILAC experiments profiling of the proteome of WT and YiaC KO E.coli
ORGANISM(S): Escherichia Coli 
2021-12-11 | PXD030346 |
MetabolomicsLactation-related metabolic mechanism investigated based on mammary gland metabolomics and 4 biofluids’ metabolomics relationships in dairy cows

BACKGROUND: Lactation is extremely important for dairy cows; however, the understanding of the underlying metabolic mechanisms is very limited. This study was conducted to investigate the inherent metabolic patterns during lactation using the overall biofluid metabolomics and the...

2018-03-16 | MTBLS411 | MetaboLights
ProteomicsA proteomic investigation of the dorsal muscle in Tibetan sheep
Firstly, the back muscle samples of Tibetan sheep of the same age were collected for subsequent proteomic analysis. The integrated and analyzed results aimed to identify proteins and pathways associated with meat quality and growth regulation in sheep, thereby providing a theoretical foundation for...
ORGANISM(S): Ovis Aries 
2024-07-26 | PXD054235 |
ProteomicsProteome-wide Hyposuccinylation of Esophageal Squamous Cell Cancer to Promotion of Tumor Metabolism and Migration
We identify abnormal protein and post-translational modification (PTM) pathways, including significantly downregulated lysine succinylation sites in cancer cells. Focusing on hyposuccinylation, we reveal that this altered PTM was enriched on enzymes of metabolic pathways inextricably linked with can...
ORGANISM(S): Homo Sapiens 
2020-09-18 | PXD021567 |
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