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TranscriptomicsscRNA-seq of stromal vascular cells from 48 week (aged) mouse subcutaneous adipose tissue compared to control 10 week (young) mouse SVF
Adipose tissue mass and adiposity change throughout the lifespan. During aging, while visceral adipose tissue (VAT) tends to increase, peripheral subcutaneous adipose tissue (SAT) decreases significantly. Unlike VAT, which is linked to metabolic diseases, SAT has beneficial effects. However, the mol...
ORGANISM(S): Mus musculus 
2021-03-25 | E-MTAB-10221 | biostudies-arrayexpress
UnknownSheng Xue Ning as a Novel Agent that Promotes SCF-Driven Hematopoietic Stem/Progenitor Cell Proliferation to Promote Erythropoiesis.
Not available
S-EPMC11429878 | biostudies-literature
UnknownThe analgesic effects of Yu-Xue-Bi tablet (YXB) on mice with inflammatory pain by regulating LXA4-FPR2-TRPA1 pathway.
Not available
S-EPMC11302111 | biostudies-literature
TranscriptomicseHSP70 promotes osteogenesis of hMSCs through activating ERK signaling pathway
Heat shock proteins are highly conserved proteins that, when produced intracellularly, protect stress exposed cells. It has been suggested that extracellular Hsp70 has both protective and deleterious effects. Our study showed eHSP70 increased the ALP activity, promoted mineralization and up-regulate...
ORGANISM(S): Homo sapiens 
2016-07-03 | E-GEOD-71080 | biostudies-arrayexpress
ProteomicsCowen_Myers_Chemogenomics_2021
This dataset consists of 4 raw MS files and associated peak lists and results files, acquired on an AB-SCIEX mass spectrometer operated in Data Dependent Acquisition mode. Samples were generated by the Cowen lab and affinity purification and mass spectrometric acquisition was performed by Zhen-Yuan...
ORGANISM(S): Candida Albicans (ncbitaxon:5476) 
2021-10-08 | MSV000088204 | MassIVE
ProteomicsClinical efficacy and biomarker analysis of stereotactic body radiotherapy combined with sintilimab and a bevacizumab biosimilar in anti-PD-1 refractory hepatocellular carcinoma
Immune checkpoint inhibitor (ICI) resistance in advanced hepatocellular carcinoma (HCC)poses a major therapeutic challenge. Here, we report a phase 2 trial evaluating stereotactic bodyradiotherapy (SBRT) combined with the anti-PD-1 antibody sintilimab and bevacizumabbiosimilar (lBI305) to re-sensiti...
ORGANISM(S): Homo sapiens (Human) 
2025-10-15 | PAD000004 | Pride
Sintilimab Bevacizumab biosimilar Anti-pd-1 refractory hepatocellular carcinoma Biomarkers of efficacy Stereotactic body radiotherapy 
UnknownL-Arginine/nitric oxide regulates skeletal muscle development via muscle fibre-specific nitric oxide/mTOR pathway in chickens.
Not available
S-EPMC9125674 | biostudies-literature
ProteomicsRegulatory Role of the VCL/ICAM-1 Pathway in Inflammatory Exudative Damage to the Gas-Blood Barrier in SARS-CoV-2 Infection: New Insights from the Omicron Paradigm
Infections by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), ranging from the initial Wildtype (WT) variant in Wuhan, China, to later variants including Omicron, have showcased a diverse spectrum of symptoms. This diversity underscores the need for ongoing exploration into the vir...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD054443 | Pride
Multi-omics  sars-cov-2  omicron  protein modification  n-glycosylation 
UnknownCNP signal pathway up-regulated in rectum of depressed rats and the interventional effect of Xiaoyaosan.
Not available
S-EPMC4316094 | biostudies-literature
TranscriptomicsExpression data from rice embryo and endosperm development
The receptor-like kinases (RLKs) plays critical roles in signal transduction through sensing the extracellular signals and activating the downstream signal transduction by phosphorylating their targets. Up to now, there are only a few RLKs have been functionally identified. In this study, we systemi...
ORGANISM(S): Oryza sativa 
2012-02-01 | E-GEOD-27856 | biostudies-arrayexpress
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