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TranscriptomicsTranscriptome analysis of cells of different cycling speed during Yamanaka reprogramming
Reprogramming somatic cells to induced pluripotency by Yamanaka factors is usually slow and inefficient, and is thought to be a stochastic process. We identified a privileged somatic cell state, from which acquisition of pluripotency could occur in a non-stochastic manner. Subsets of murine hematopo...
ORGANISM(S): Mus musculus 
2014-02-12 | E-GEOD-53074 | biostudies-arrayexpress
UnknownA PIANO (Proper, Insufficient, Aberrant, and NO Reprogramming) Response to the Yamanaka Factors in the Initial Stages of Human iPSC Reprogramming.
Not available
S-EPMC7246695 | biostudies-literature
UnknownSpecific Activation of Yamanaka Factors via HSF1 Signaling in the Early Stage of Zebrafish Optic Nerve Regeneration.
Not available
S-EPMC9961437 | biostudies-literature
UnknownSynthesis of alkyl levulinates <i>via</i> the esterification of levulinic acid and transesterification of methyl levulinate with alkyl alcohols over montmorillonite K10.
Not available
S-EPMC12044522 | biostudies-literature
UnknownThe Active Center of Co-N-C Electrocatalysts for the Selective Reduction of CO2 to CO Using a Nafion-H Electrolyte in the Gas Phase.
Not available
S-EPMC7424585 | biostudies-literature
UnknownDimerization site 2 of the bacterial DNA-binding protein H-NS is required for gene silencing and stiffened nucleoprotein filament formation.
Not available
S-EPMC6005454 | biostudies-literature
TranscriptomicsGeneration of Induced Pluripotent Stem Cells using Recombinant Proteins
Groundbreaking work demonstrated that ectopic expression of four transcription factors, Oct4, Klf4, Sox2, and c-Myc, could reprogram murine somatic cells to induced pluripotent stem cells (iPSCs) (Takahashi and Yamanaka, 2006), and human iPSCs were subsequently generated using similar genetic manipu...
ORGANISM(S): Mus musculus 
2010-04-09 | E-GEOD-16062 | biostudies-arrayexpress
UnknownDynamic regulation of human endogenous retroviruses mediates factor-induced reprogramming and differentiation potential.
Not available
S-EPMC4151758 | biostudies-literature
TranscriptomicsMolecular insights into induced pluripotency mediated by the OCT4, SOX2, KLF and c-MYC gene regulatory network
Human somatic fibroblasts can be reprogrammed to induced pluripotent stem (iPS) cells by exogenic expression of the Yamanaka factors (OCT4, SOX2, KLF4 and MYC) after about 1 month. To gain some insight into the early processes operative in fibroblast reprogramming, we profiled genome-wide transcript...
ORGANISM(S): Homo sapiens 
2011-10-24 | E-GEOD-28688 | biostudies-arrayexpress
TranscriptomicsMolecular insights into induced pluripotency mediated by the OCT4, SOX2, KLF and c-MYC gene regulatory network
Human somatic fibroblasts can be reprogrammed to induced pluripotent stem (iPS) cells by exogenic expression of the Yamanaka factors (OCT4, SOX2, KLF4 and MYC) after about 1 month. To gain some insight into the early processes operative in fibroblast reprogramming, we profiled genome-wide transcript...
ORGANISM(S): Homo sapiens 
2011-10-25 | GSE28688 | GEO
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