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We have previously shown that pluripotent stem cells are induced from mouse fibroblasts by retroviral introduction of Oct3/4, Sox2, c-Myc and Klf4, and subsequent selection for Fbx15 expression. These iPS (induced pluripotent stem) cells are similar to embryonic stem (ES) cells in morphology, prolif...
ORGANISM(S): Mus musculus 
This SuperSeries is composed of the following subset Series: GSE31581: ECAT15-2/Dppa2 deficient ESCs GSE31582: ECAT15-2/Dppa2 transgenic rescue into ECAT15-2/Dppa2 deficient ESCs GSE31583: Lung of ECAT15-2/Dppa2 deficient embryo at E18.5 Refer to individual Series
ORGANISM(S): Mus musculus 
Many transcription factors and DNA binding proteins play essential roles in the development of organs in which they are highly and/or specifically expressed. Embryonic stem cell (ESC) associated transcript (ECAT) 15-1 and ECAT15-2, also known as developmental pluripotency-associated (Dppa) 4 and Dpp...
ORGANISM(S): Mus musculus 
Many transcription factors and DNA binding proteins play essential roles in the development of organs in which they are highly and/or specifically expressed. Embryonic stem cell (ESC) associated transcript (ECAT) 15-1 and ECAT15-2, also known as developmental pluripotency-associated (Dppa) 4 and Dpp...
ORGANISM(S): Mus musculus 
p53 knockdown by shRNA markedly increased efficiency of human iPS cell generation Gene expression patterns were compared between human ES cells and dermal fibroblasts. Gene expression patterns were also compared between p53 shRNA-treated fibroblasts and control fibroblasts.
ORGANISM(S): Homo sapiens 
This SuperSeries is composed of the following subset Series: GSE13312: Role of p53 in mouse iPS cell generation GSE13334: Effect of p53 in human iPS cell generation Refer to individual Series
ORGANISM(S): Homo sapiens 
Many transcription factors and DNA binding proteins play essential roles in the development of organs in which they are highly and/or specifically expressed. Embryonic stem cell (ESC) associated transcript (ECAT) 15-1 and ECAT15-2, also known as developmental pluripotency-associated (Dppa) 4 and Dpp...
ORGANISM(S): Mus musculus 
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
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