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MetabolomicsNiacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma (Cell NAMPTi treatment)

NAMPT plays a major role in NAD biosynthesis in many cancers and is an attractive potential cancer target. However, factors dictating therapeutic efficacy of NAMPT inhibitors (NAMPTi) are unclear. We report that neuroendocrine phenotypes predict lung and prostate carcinoma vulnerability to NAMPTi...

2023-10-10 | MTBLS7251 | MetaboLights
MetabolomicsNiacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma (Mouse NAMPT targeted therapy)

NAMPT plays a major role in NAD biosynthesis in many cancers and is an attractive potential cancer target. However, factors dictating therapeutic efficacy of NAMPT inhibitors (NAMPTi) are unclear. We report that neuroendocrine phenotypes predict lung and prostate carcinoma vulnerability to NAMPTi...

2023-10-10 | MTBLS7252 | MetaboLights
MetabolomicsNiacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma (Mouse NAD targeted time-course)

NAMPT plays a major role in NAD biosynthesis in many cancers and is an attractive potential cancer target. However, factors dictating therapeutic efficacy of NAMPT inhibitors (NAMPTi) are unclear. We report that neuroendocrine phenotypes predict lung and prostate carcinoma vulnerability to NAMPTi...

2023-10-10 | MTBLS7253 | MetaboLights
UnknownVariants in the BACH2 and CLEC16A gene might be associated with susceptibility to insulin-triggered type 1 diabetes.
Not available
S-EPMC6825945 | biostudies-literature
UnknownDedifferentiation of human primary thyrocytes into multilineage progenitor cells without gene introduction.
Not available
S-EPMC3083435 | biostudies-literature
GenomicsHigh-throughput sequence data of ChIP performed with anti-SMARCAD1 (ASNA) or anti-CBP actibodies.
Histone acetylation and nucleosome remodeling play a pivotal role in transcriptional regulation. While histone acetylase and ATP-dependent chromatin remodeling activities have been well characterized, how the two activities are coordinated remains to be uncovered. We discovered ATP-dependent histone...
ORGANISM(S): Drosophila melanogaster 
2016-03-17 | E-GEOD-72666 | biostudies-arrayexpress
UnknownExtracellular RNA clearance by non-canonical cell-surface MDA5 protects against lung fibrosis.
Not available
S-SCDT-10_1038-S44321-026-00513-6 | biostudies-other
ProteomicsProteomic analysis of ascites from LC and GC patients
Proteomic analysis by mass spectrometry was performed to characterize proteins in ascites samples from patients with gastric cancer (N = 7) or liver cirrhosis (N = 3).
ORGANISM(S): Homo Sapiens (human) 
2023-10-07 | PXD037200 | JPOST Repository
UnknownCommunity-Level Compact City Design, Health Care Provision, and Outcomes of Patients With Stroke.
Not available
S-EPMC12449981 | biostudies-literature
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