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UnknownBoth high-fidelity replicative and low-fidelity Y-family polymerases are involved in DNA rereplication.
Not available
S-EPMC4301717 | biostudies-literature
TranscriptomicsA key role for neuropeptide Y in lifespan extension and cancer suppression by dietary restriction
Key molecules that modulate the effect of dietary restriction (DR), a well-known laboratory intervention for longevity in organisms, remain elusive in mammals. We evaluated neuropeptide Y (Npy), which is involved in the physiological adaptation to energy deficits, for its role in the effects of DR. ...
ORGANISM(S): Mus musculus 
2013-02-28 | E-GEOD-42761 | biostudies-arrayexpress
TranscriptomicsAcyclic retinoid targets platelet-derived growth factor signaling in the prevention of hepatic fibrosis and hepatocellular carcinoma development
Gene expression profiling in non tumor lesion in the liver of patients prior to administering peretinoin was unrelated to the clinical outcome, however, gene expression profiling 8 weeks after starting peretinoin therapy significantly predicted the recurrence of HCC Peretinoin, a member of the acycl...
ORGANISM(S): Homo sapiens 
2012-08-19 | E-GEOD-29302 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human CD133+ immature blasts from patients with AML/RAEB
CD133-positive immature blasts were purified from bone marrow of the patients. Total RNA was extracted by RNeasy mini spin column (Qiagen, Inc). SUBMITTER_CITATION: Yamashita Y, Ohashi J, Hirai Y, Choi YL, Kaneda R, Fujiwara S-i, Arai Y, Akutsu M, Tsutsumi C, Miyazaki Y, Usuki K, Teramura M, Mitani ...
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-1427 | biostudies-arrayexpress
UnknownA maternally programmed intergenerational mechanism enables male offspring to make piRNAs from Y-linked precursor RNAs in Drosophila.
Not available
S-EPMC10567549 | biostudies-literature
UnknownA key role for neuropeptide Y in lifespan extension and cancer suppression via dietary restriction.
Not available
S-EPMC3970128 | biostudies-literature
UnknownY-box binding protein YBX1 and its correlated genes as biomarkers for poor outcomes in patients with breast cancer.
Not available
S-EPMC6324687 | biostudies-literature
UnknownA quasi-stable molybdenum sub-oxide with abundant oxygen vacancies that promotes CO2 hydrogenation to methanol.
Not available
S-EPMC8317622 | biostudies-literature
ProteomicsLithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal
Tobe BTD, Crain AM, Winquist AM, Calabrese B, Makihara H, Zhao W, Lalonde J, Nakamura H, Konopaske G, Sidor M, Pernia C, Yamashita N, Wada M, Inoue Y, Nakamura F, Sheridan SD, Logan R, Brandel M, Wu D, Hunsberger J, Dorsett L, Duerr C, Basa RCB, McCarthy MJ, Udeshi N, Mertins P, Carr SA, Rouleau G, ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-04-21 | MSV000080975 | MassIVE
MetabolomicsNiacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma (Cell NAMPTi treatment)

NAMPT plays a major role in NAD biosynthesis in many cancers and is an attractive potential cancer target. However, factors dictating therapeutic efficacy of NAMPT inhibitors (NAMPTi) are unclear. We report that neuroendocrine phenotypes predict lung and prostate carcinoma vulnerability to NAMPTi...

2023-10-10 | MTBLS7251 | MetaboLights
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