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ProteomicsChapman_CCM_2018
This submission contains the mass spectrometry files for the manuscript by Chapman and colleagues that characterize KRI-1 in C. elegans by affinity purification experiments of KRI-1 fused to GFP. Controls used for this experiment include ACT-5 fused to GFP and N2 worms. This dataset consists of 18 ...
ORGANISM(S): Caenorhabditis Elegans (ncbitaxon:6239) 
2018-05-24 | MSV000082400 | MassIVE
ProteomicsAdaptive evolution of Methylotuvimicrobium alcaliphilum to grow in the presence of rhamnolipids improves fatty acid and rhamnolipid production from CH4
Rhamnolipids (RL) are well-studied biosurfactants naturally produced by pathogenic strains of P. aeruginosa. Current methods to produce RLs in native and heterologous hosts have focused on carbohydrates as production substrate; however CH4 provides an intriguing alternative as a substrate for RL pro...
ORGANISM(S): Methylomicrobium alcaliphilum (strain DSM 19304 / NCIMB 14124 / VKM B-2133 / 20Z) 
2022-09-19 | PXD029605 | Pride
Methylotuvimicrobium alcaliphilum Adaptive laboratory evolution Rhamnolipids Ch4 
UnknownFeasibility Trial of Tailored Home Modifications: Process Outcomes.
Not available
S-EPMC5744715 | biostudies-literature
MetabolomicsAirway Dysbiosis Accelerates Lung Function Decline in Chronic Obstructive Pulmonary Disease (Human UPLC-MS/MS assays)

Progressive decline in lung function is a hallmark of chronic obstructive pulmonary disease (COPD). Although airway dysbiosis occurs in COPD, whether it contributes to disease progression remains unknown. Here, through a longitudinal analysis on 181 COPD individuals from two large cohorts involvi...

2023-06-12 | MTBLS5423 | MetaboLights
ProteomicsEngineering Corynebacterium glutamicum to produce the biogasoline isopentenol from plant biomass hydrolysates
Background. Many microbial hosts used for the rapid discovery and development of metabolic pathways can have sensitivities to final products and process reagents. Isopentenol, a biogasoline candidate, has an established heterologous gene pathway but is toxic to many microbial hosts. Reagents used in...
ORGANISM(S): Corynebacterium Glutamicum Atcc 13032 
PXD012293 | panorama
MetabolomicsSCP4-STK35/PDIK1L complex is a dual phospho-catalytic signaling dependency in acute myeloid leukemia
Acute myeloid leukemia (AML) cells rely on phospho-signaling pathways to gain unlimited proliferation potential. Here, we used domain-focused CRISPR screening to identify the nuclear phosphatase SCP4 as a dependency in AML, yet this enzyme is dispensable in normal hematopoietic progenitor cells. Usi...
2025-05-29 | MTBLS3707 | MetaboLights
TranscriptomicsTargeted disruption of BMAL1 in the peripheral reproductive axis results in infertility in female mice
The product of the Bmal1 locus is an essential component of the circadian clock that plays important roles in various aspects of reproductive biology,and when disrupted results in infertility. In an effort to establish the identity of the tissue specific clock that is responsible for this infertilit...
ORGANISM(S): Mus musculus 
2014-10-01 | E-GEOD-48758 | biostudies-arrayexpress
UnknownModeling Postoperative Nerve Regeneration Using Diffusion MRI: A Preclinical Study of a Novel Mathematical Approach.
Not available
S-EPMC12803670 | biostudies-literature
UnknownC1q/TNF-Related Protein 3 Prevents Diabetic Retinopathy via AMPK-Dependent Stabilization of Blood-Retinal Barrier Tight Junctions.
Not available
S-EPMC8909652 | biostudies-literature
TranscriptomicsmiRNA profiling of 39 human AML samples
'miRNA expression in 39 human AML samples was analyzed on Sureprint G3 Human miRNA (release 16.0) 8x60K Microarrays from Agilent Technologies. Half the samples represent primary AMLs while the other half represents secondary AMLs. Sample material consisted of cryopreserved bone marrow or blood aspir...
ORGANISM(S): Homo sapiens 
2020-12-31 | E-MTAB-3627 | biostudies-arrayexpress
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