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UnknownIntegration of HiBiT into enteroviruses: A universal tool for advancing enterovirus virology research.
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S-EPMC11279724 | biostudies-literature
ProteomicsPharmacological targeting of the mitochondrial phosphatase PTPMT1 sensitizes hepatocellular carcinoma to ferroptosis
Protein tyrosine phosphatase mitochondrial 1 (PTPMT1), is a member of the protein tyrosine phosphatase superfamily localized on the mitochondrial inner membrane, and regulates the biosynthesis of cardiolipin. Given the important position of PTPMT1 in mitochondrial function and metabolism, pharmacolo...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD058606 | Pride
Ptpmt1  mitochondria  ferroptosis  tca cycle  hepatocellular carcinoma 
ProteomicsPotential binding proteins of CAV3 obtained from LC-MS/MS
To gain further insight into the molecular mechanisms of CAV3 in DCM. we conducted liouid chromatography-tandem mass spectrometry (LC-MS/MSassays to identify potential binding proteins of CAV3 in cardiomyocytes.LC-MS/MS was conducted by SpecAly Life Technology Co, Ltd. (Wuhan, China).
ORGANISM(S): Homo Sapiens 
2023-08-21 | PXD044674 |
ProteomicsTrimodal probe for proteome profiling of AchE in animals
Acetylcholinesterase (AChE) is a cholinergic enzyme that hydrolyzes esters of the neurotransmitter acetylcholine (Ach). Aberrant activity of AChE is closely associated with various neurodegenerative diseases and cancer. Current chemical probes for AChE detection mostly rely on fluorescence readout a...
ORGANISM(S): Mus Musculus 
2025-04-24 | PXD063264 |
ProteomicsLysine-targeting, covalent inhibitors of bromodomain BD1 of BET proteins in live cells and animals
We report herein a set of activity-based probes (ABPs; P3-P7) based on various lysine-reactive covalent warheads capable of global profiling of ligandable lysine within BRDs in live cells and animals. Chemoproteomic experiments with P7 by utilizing 2-ethynylbenzaldehyde (EBA) identified 18 endogenou...
ORGANISM(S): Homo Sapiens Mus Musculus 
2025-04-10 | PXD058513 |
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