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UnknownEpigenetics meets genetics in acute myeloid leukemia: clinical impact of a novel seven-gene score.
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S-EPMC3918538 | biostudies-literature
TranscriptomicsExpression and metylation data from A2780 (cisplatin-sensitive) and Round5 A2780 (cisplatin-resistant) cell lines
This SuperSeries is composed of the following subset Series: GSE15372: Expression data from A2780 (cisplatin-sensitive) and Round5 A2780 (cisplatin-resistant) cell lines. GSE15373: Promoter CpG island methylation data from A2780 (cisplatin-sensitive) and Round5 A2780 (cisplatin-resistant) cell lines...
ORGANISM(S): Homo sapiens 
2009-04-17 | E-GEOD-15709 | biostudies-arrayexpress
TranscriptomicsEstrogen-mediated Epigenetic Repression of Large Chromosomal Regions through DNA Looping
The current concept of epigenetic repression is based on one repressor unit corresponding to one silent gene. This notion, however, cannot adequately explain concurrent silencing of multiple loci observed in large chromosome regions. The long-range epigenetic silencing (LRES) can be a frequent occur...
ORGANISM(S): Homo sapiens 
2010-04-29 | E-GEOD-21068 | biostudies-arrayexpress
TranscriptomicsDNMT3B targets in RKO cells by ChIP-on-chip
Chromatin immunoprecipitation with DNMT3B specific antibody followed by CGI microarray identified genes with or without CGIs, repeat elements and genomic contigs in RKO cells. ChIP-Chop analysis showed that majority of the target genes including P16, DCC, DISC1, SLIT1, CAVEOLIN1, TBX5, TBX18, HOXB1...
ORGANISM(S): Homo sapiens 
2010-05-06 | E-GEOD-18929 | biostudies-arrayexpress
TranscriptomicsGenome-wide expression screening discloses long noncoding RNAs involved in thyroid carcinogenesis
Context: Long non-coding RNAs (lncRNAs) regulate pathological processes, yet their potential roles in papillary thyroid carcinoma (PTC) are poorly understood. Objective: To profile transcriptionally dysregulated lncRNAs in PTC and identify lncRNAs associated with clinicopathological characteristics....
ORGANISM(S): Homo sapiens 
2016-08-03 | E-GEOD-83520 | biostudies-arrayexpress
TranscriptomicsExpression and Prognostic impact of LncRNAs in AML
Long noncoding RNAs (lncRNAs) are transcripts longer than 200 nucleotides located within the intergenic stretches or overlapping antisense transcripts of protein coding genes. LncRNAs are involved in numerous biological roles including imprinting, epigenetic regulation, apoptosis and cell-cycle. To ...
ORGANISM(S): Homo sapiens 
2014-11-26 | E-GEOD-63614 | biostudies-arrayexpress
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