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LIN28 is a conserved RNA binding protein implicated in pluripotency, reprogramming and oncogenesis. Previously shown to act primarily by blocking let-7 microRNA (miRNA) biogenesis, here we elucidate distinct roles of LIN28 regulation via its direct messenger RNA (mRNA) targets. Through cross-linking...
ORGANISM(S): Homo sapiens 
TMT10plex-labeled, phospho-enriched, fractionated sample from the hippocampus of the NPC1-null mouse model was collected using nanoflow-LC-MS. Our goal is to identify signaling changes at an early time-point in the NPC1-null mouse model.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
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