Sort   by:  
 Page size 
ProteomicsIdentification of a 144-amino-acid Scaffold Protein for Extracellular Vesicle Engineering
Extracellular vesicles (EVs) have emerged as promising drug-delivery vehicles. Genetic engineering of a membrane-bound, EV-sorting scaffold protein empowers these cell-borne nanosized vesicles by installing targeting moieties on the surface and enriching therapeutic cargo in the lumen. However, the ...
ORGANISM(S): Homo sapiens (Human) 
2026-04-27 | PXD057965 | Pride
Expi293f-evs Lc-s/ms 
UnknownDiscovery of Isoindoline Amide Derivatives as Potent and Orally Bioavailable ADAMTS-4/5 Inhibitors for the Treatment of Osteoarthritis.
Not available
S-EPMC9274773 | biostudies-literature
UnknownDiscovery of a novel RORγ antagonist with skin-restricted exposure for topical treatment of mild to moderate psoriasis.
Not available
S-EPMC8080595 | biostudies-literature
UnknownSHR1032, a novel STING agonist, stimulates anti-tumor immunity and directly induces AML apoptosis.
Not available
S-EPMC9122897 | biostudies-literature
ProteomicsProteomic analysis of developing grains in the wheat under drought stress
In this study, we performed the first dynamic proteome analysis of developing grains in the wheat-Thinopyrum intermedium 7XL/7DS translocation line under drought stress using a two-dimensional difference gel electrophoresis (2D-DIGE) based proteomic approach.
ORGANISM(S): Triticum Aestivum 
2021-11-28 | PXD030025 |
ProteomicsLactylation of NAT10 promotes N4‐acetylcytidine modification on tRNASer-CGA-1-1 to boost oncogenic DNA virus KSHV reactivation
N4-acetylcytidine (ac4C), a conserved but recently rediscovered RNA modification on tRNAs, rRNAs and mRNAs, is catalyzed by N-acetyltransferase 10 (NAT10). Lysine acylation is a ubiquitous protein modification that controls protein functions. Our latest study demonstrates a NAT10-dependent ac4C modi...
ORGANISM(S): Homo Sapiens 
PXD049447 |
ProteomicsSilicon-rhodamine-enabled Identification (SeeID) for Near-Infrared Light Controlled Proximity Labeling In Vitro and In Vivo
Advancement in fluorescence imaging techniques enables the study of protein dynamics and localization with unprecedented spatiotemporal resolution. However, current imaging tools are unable to elucidate dynamic protein interactomes underlying imaging observations. In contrast, proteomics tools such ...
ORGANISM(S): Homo Sapiens Mus Musculus 
PXD067243 |
ProteomicsMecicago truncatula pulvinus proteomics
the pulvinus proteomics of Mecicago truncatula A17
ORGANISM(S): Medicago Truncatula 
PXD028750 |
ProteomicsA prokaryotic E2 enzyme imitates the ubiquitin pathway to regulate the antiviral cGAS
The cyclic oligonucleotide-based anti-phage signalling system (CBASS) is a typeof innate prokaryotic immune system. Composed of a cyclic GMP-AMP synthase (cGAS) and CBASS-associated proteins, CBASS utilizes cyclic oligonucleotides to activate antiviral immunity. One major class of CBASS contains a h...
ORGANISM(S): Serratia Marcescens Lct-sm213 
2024-02-27 | PXD050178 |
UnknownFine mapping of genetic variants in BIN1, CLU, CR1 and PICALM for association with cerebrospinal fluid biomarkers for Alzheimer's disease.
Not available
S-EPMC3036586 | biostudies-literature
Sort   by:  
 Page size