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UnknownA machine learning-based predictive model for complication risks in vacuum-assisted breast biopsy.
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S-EPMC12450878 | biostudies-literature
ProteomicsProteomics of Esophageal Squamous Cell Carcinoma Response to anti-PD1 Immunotherapy Response
Immunotherapy has revolutionized cancer treatment, yet many patients do not respond. Here, we profile the proteome and phosphoproteome of clinical pre-treatment samples from 73 esophageal squamous cell carcinoma (ESCC) patients undergoing anti-programmed death 1 (PD1) immunotherapy.
ORGANISM(S): Homo Sapiens 
2026-03-31 | PXD076423 |
ProteomicsQuartet Protein Reference Materials for Multi-platform Assessment of Label-free Proteomics
We developed the Quartet as a bulk of proteome reference materials with built-in truth, and distributed the same aliquots to 15 laboratories in six cities of China with nine conventional LC-MS/MS platforms. Relative protein abundances from over 12,000 proteins on 816 MS files were obtained and compa...
ORGANISM(S): Homo Sapiens 
2023-06-24 | PXD043262 |
ProteomicsProteomic characterization of the colorectal cancer response to chemoradiation and targeted therapies
Herein, we assembled a cohort composed of 254 CRC patients, including discovery cohort (N = 124) and validation cohort (N = 130), which received either chemotherapy (mainly FOLFOX therapy), chemoradiotherapy (mainly FOLFOX combined with radiotherapy), or targeted combination therapy (mainly FOLFOX c...
ORGANISM(S): Homo Sapiens 
2023-10-30 | PXD046566 |
ProteomicsProteogenomics of diffuse gliomas reveal molecular subtypes associated with specific therapeutic targets and immune-evasion mechanisms
This dataset include the proteomic data of 243 glioma tumor tissues (discovery: 187, validation: 56); 56 tumor-adjacent tissues (discvoery: 35, validation: 21); 12 normal brain tissues; corresponding phosphoproteomic data
ORGANISM(S): Homo Sapiens 
2022-12-12 | PXD038732 |
ProteomicsProteomics of the Gastric cancer Response to anti-PD1 therapy
To validate the correlation between Th1/Th2 ratio and immunotherapeutic effectiveness, we collected a group of GC patients treated with anti-PD1 therapy, including 7 responder cases (PR) and 7 non-responder cases (SD/PD). The formalin-fixed paraffin-embedded (FFPE) tumor tissue sections derived from...
ORGANISM(S): Homo Sapiens 
2022-11-17 | PXD038188 |
ProteomicsMultilevel proteomic analyses reveal molecular diversity between diffuse-type and intestinal-type gastric cancer
We report a comprehensive proteomic analysis of diffuse-type gastric cancer (DGC) (n=83), intestinal-type gastric cancer (IGC) (n=102), mixed-type gastric cancer (MGC) (n=11), and paired normal adjacent tissues (NATs), including data obtained by proteomics, phospho-proteomics profiling and TFs activ...
ORGANISM(S): Homo Sapiens 
2022-11-18 | PXD038214 |
ProteomicsProteomics of the Gastric cancer Response to Chemotherapy
Herein, we set out to investigate the responses to first-line therapies (DOS, XELOX, and anti-HER2-based therapies) for GC through a comprehensive proteomic analysis. We constructed a GC cohort that covered three clinical therapy subcohorts, including a DOS subcohort (44 patients treated with DOS th...
ORGANISM(S): Homo Sapiens 
2022-09-09 | PXD024255 |
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