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UnknownCdk5 phosphorylation-induced SIRT2 nuclear translocation promotes the death of dopaminergic neurons in Parkinson's disease.
Not available
S-EPMC9021196 | biostudies-literature
UnknownTowards early risk biomarkers: serum metabolic signature in childhood predicts cardio-metabolic risk in adulthood.
Not available
S-EPMC8511803 | biostudies-literature
TranscriptomicsTranscriptomic analyses of Myc-induced zebrafish liver cancer
To study the characteristics and mechanisms of Myc-induced zebrafish liver tumor, next-generation sequencing-based SAGE analyses were used to examine the transcriptomes of tumor and control samples. The results indicated that ribosome proteins were overwhelmingly up-regulated in the Myc-induced live...
ORGANISM(S): Danio rerio 
2013-04-02 | E-GEOD-40745 | biostudies-arrayexpress
UnknownProteome-wide Mendelian randomization and colocalization analysis identify therapeutic targets for stroke.
Not available
S-EPMC12211327 | biostudies-literature
ProteomicsIntegrated proteomic and N-glycoproteomic analyses of human breast cancer
In the present study, we systematically profiled proteomes and N-glycoproteomes of cancerous, paracancerous, and distal noncancerous tissues from patients with breast cancer by DIA.
ORGANISM(S): Homo Sapiens 
2020-04-30 | PXD017358 |
ProteomicsNovel molecular glue degraders against broad range of myeloma and lymphoma cancer cell lines
Targeted protein degradation of neosubstrates plays a crucial role in treating hematological cancers with IMiDs therapy. However, the inevitable drug resistance and hematological toxicities remain persistent challenges, limiting their clinical efficacy. Herein, we present the discovery of a lead deg...
ORGANISM(S): Homo Sapiens 
2024-06-22 | PXD053334 |
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