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ProteomicsSelective Binding of a Toxin and Phosphatidylinositides to a Mammalian Potassium Channel
G-protein-gated inward rectifying potassium channels (GIRKs) require Gβγ subunits and phosphorylated phosphatidylinositides (PIPs) for gating. Although studies have provided insight into these interactions, the mechanism of how these events are modulated by Gβγ and the binding affinity between PIPs ...
ORGANISM(S): Mus musculus (Mouse) 
2019-04-02 | PXD012894 | Pride
Potassium channel Pip2 Lipid selectivity Lipid binding Girk2 Phosphorylation 
TranscriptomicsColon tissue of Il10-/- mice monoassociated with Escherichia coli NC101 or NC101-delta-pks
We observed that deletion of polyketide synthase (pks) from E. coli NC101 reduces its ability to induce tumors in interleukin-10 knockout (Il10-/-) mice injected with azoxymethane (AOM), without altering histologic inflammation. The goal of this experiment is to assess inflammatory cytokine levels i...
ORGANISM(S): Mus musculus 
2012-07-04 | E-GEOD-39095 | biostudies-arrayexpress
UnknownGalectin-3 promotes HIV-1 budding via association with Alix and Gag p6.
Not available
S-EPMC4181451 | biostudies-literature
TranscriptomicsTranscription profiling of liver, kidney and brain from male and female Zebra Finches
Each array hybridization involved one male sample hybridized in competition to one female sample. For each hybridization one sample was labeled with Cy5 and the other with Cy3. Half of the male samples were labeled with Cy5 and rest with Cy3. Each hybridization was tissue-specific (i.e., hybridiz...
ORGANISM(S): Taeniopygia guttata 
2007-02-15 | E-MEXP-543 | biostudies-arrayexpress
UnknownMEK inhibitor GSK1120212-mediated radiosensitization of pancreatic cancer cells involves inhibition of DNA double-strand break repair pathways.
Not available
S-EPMC4825728 | biostudies-literature
UnknownThe machine learning-powered BirdNET App reduces barriers to global bird research by enabling citizen science participation.
Not available
S-EPMC9239458 | biostudies-literature
UnknownCharacterization of Niemann-Pick Type C2 protein expression in multiple cancers using a novel NPC2 monoclonal antibody.
Not available
S-EPMC3798307 | biostudies-literature
UnknownPassive acoustic monitoring can provide insights into occupancy dynamics and impacts of disturbance for at-risk species.
Not available
S-EPMC12808558 | biostudies-literature
UnknownLCL161, a SMAC-mimetic, Preferentially Radiosensitizes Human Papillomavirus-negative Head and Neck Squamous Cell Carcinoma.
Not available
S-EPMC6548673 | biostudies-literature
UnknownMicroRNA signature for estimating the survival time in patients with bladder urothelial carcinoma.
Not available
S-EPMC8907292 | biostudies-literature
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