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MetabolomicsPhotosystem - driven resilience of green microalga Tetraselmis chuii toward acute nonylphenol stress

Anthropogenic chemicals pose a threat to aquatic ecosystems by targeting the microalgal photosynthetic engines that drive primary production. Although the toxic effects of pollutants such as nonylphenol (NP) are well-acknowledged, the molecular mechanisms enabling microalgal resilience remain lar...

2026-01-29 | MTBLS13769 | MetaboLights
ProteomicsPhosphoproteomics reveals the disturb of kinase-substrates in intracerebral hemorrhage with hyperhomocysteinaemia
To elucidate the impact and mechanism of homocysteine on intracerebral hemorrhage at a system-wide level, we used a global phosphoproteomic approach combined with proteomics. Hyperhomocysteinaemia (HHcy) mice was induced by high methionine diet，and Experimental intracerebral hemorrhage was induced ...
ORGANISM(S): Mus Musculus 
2023-01-31 | PXD039748 |
ProteomicsFusobacterium nucleatum Promotes PD-L1 Expression in Macrophages by Inducing Exosomal lncRNA MANCR from Colorectal Cancer Cells
This mass spectrometry dataset was generated from RNA pull-down assays to identify proteins interacting with lncRNA MANCR in colorectal cancer cells (HCT116) and macrophages (THP-1)
ORGANISM(S): Homo Sapiens 
2026-01-04 | PXD072638 |
ProteomicsTransketolase promotes MAFLD by limiting inosine-induced mitochondrial activity (Proteomics)
Metabolic dysfunction-associated fatty liver disease (MAFLD) has a global prevalence of about 25% and no approved therapy. Using metabolomic and proteomic analyses, we identified high expression of hepatic transketolase (TKT), a metabolic enzyme of the pentose phosphate pathway, in human and mouse M...
ORGANISM(S): Homo Sapiens 
2024-02-26 | PXD050130 |
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