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GenomicsNHLBI GO-ESP: Family Studies (Familial Interstitial Pneumonia)

The NHLBI "Grand Opportunity" Exome Sequencing Project (GO-ESP), a signature project of the NHLBI Recovery Act investment, was designed to identify genetic variants in coding regions (exons) of the human genome (the "exome") that are associated with heart, lung and blood diseases. These and relat...

phs000582.v1.p1 | EGA
TranscriptomicsAKT network of genes and impaired myocardial contractility during murine acute chagasic myocarditis
Rationale: Chagasic disease is associated with high morbidity in Latin America. Acute Chagasic myocarditis is consistently found in acute infections but little is known about its contribution to chronic cardiomyopathy. The aim of the study was to phenotypically characterize two strains of mice with ...
ORGANISM(S): Mus musculus 
2014-12-05 | E-GEOD-63847 | biostudies-arrayexpress
TranscriptomicsDietary folate depletion and repletion in C57BL/6J mice, ApoE knockout mice, and choline supplemented C57BL/6J mice
Defects in homocysteine and folate metabolism are associated with increased risks for neural tube and congenital heart defects, cardiovascular disease and stroke, cancers, and neurodegeneration. In many but not all cases, dietary supplementation with folate significantly reduces the severity and in...
ORGANISM(S): Mus musculus 
2008-08-27 | E-GEOD-9243 | biostudies-arrayexpress
TranscriptomicsDietary folate depletion and repletion in A/J and C57BL/6J mice
Defects in homocysteine and folate metabolism are associated with increased risks for neural tube and congenital heart defects, cardiovascular disease and stroke, cancers, and neurodegeneration. In many but not all cases, dietary supplementation with folate significantly reduces the severity and in...
ORGANISM(S): Mus musculus 
2008-08-27 | E-GEOD-9242 | biostudies-arrayexpress
TranscriptomicsDietary folate depletion and repletion
This SuperSeries is composed of the following subset Series: GSE9242: Dietary folate depletion and repletion in A/J and C57BL/6J mice GSE9243: Dietary folate depletion and repletion in C57BL/6J mice, ApoE knockout mice, and choline supplemented C57BL/6J mice Keywords: SuperSeries Refer to individual...
ORGANISM(S): Mus musculus 
2010-06-20 | E-GEOD-9245 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of liver from Dahl salt sensitive (SS) rats and SS9BN consomic rats during hypoxia treatment
Examination of gene expression associated with hypoxia treatment of parental salt sensitive (SS) and consomic Brown Norway (SS9BN) rat strain. SS9BN rats are derived from introgression of chromosome 9 from BN rats into the SS genetic background.
ORGANISM(S): Rattus norvegicus 
2006-09-15 | E-TIGR-126 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of lung from Dahl salt sensitive (SS) rats and SS9BN consomic rats during hypoxia treatment
Examination of gene expression associated with hypoxia treatment of parental salt sensitive (SS) and consomic Brown Norway (SS9BN) rat strain. SS9BN rats are derived from introgression of chromosome 9 from BN rats into the SS genetic background.
ORGANISM(S): Rattus norvegicus 
2006-09-15 | E-TIGR-127 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of lung from Dahl salt sensitive (SS) rats and SS11BN consomic rats during hypoxia treatment
Examination of gene expression changes during hypoxia of the Dahl salt sensative (SS) rat and SS11BN consomic rat. SS11BN rats are derived from introgression of chromosome 11 from Brown Norway (BN) rat into the SS genetic background.
ORGANISM(S): Rattus norvegicus 
2006-09-15 | E-TIGR-116 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of heart during hypoxia of the Fawn Hooded Hypertensive (FHH) rat and FHH12BN consomic rat
Examination of gene expression changes during hypoxia of the Fawn Hooded Hypertensive (FHH) rat and FHH12BN consomic rat. FHH12BN rats are derived from introgression of chromosome 12 and from the Brown Norway (BN) rat into the FHH genetic background.
ORGANISM(S): Rattus norvegicus 
2006-09-15 | E-TIGR-111 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of lung from Dahl salt sensitive (SS) rats and SS4BN consomic rats during hypoxia treatment
Examination of gene expression changes during hypoxia of the Dahl salt sensative (SS) rat and SS4BN consomic rat. SS4BN rats are derived from introgression of chromosome 4 from Brown Norway (BN) rat into the genetic background.
ORGANISM(S): Rattus norvegicus 
2006-09-15 | E-TIGR-118 | biostudies-arrayexpress
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