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TranscriptomicsGene expression in epithelial and non-epithelial cells of renal origin
We aimed to define epithelial-specific genes in the kidney. In the developing mouse kidney at E12.5 epithelial cells are restricted to the ureteric bud, while mesenchymal cells surrounding the ureteric bud are non-epithelial. The mouse renal epithelial cell line mIMCD-3 was used to represent kidney ...
ORGANISM(S): Mus musculus 
2010-09-23 | E-GEOD-24295 | biostudies-arrayexpress
UnknownJia-Wei-Kai-Xin-San Treatment Alleviated Mild Cognitive Impairment through Anti-Inflammatory and Antiapoptotic Mechanisms in SAMP8 Mice.
Not available
S-EPMC10635749 | biostudies-literature
MetabolomicsDifferential role of sphingomyelin in influenza virus, rhinovirus and SARS-CoV-2 infection of Calu-3 cells
Host cell lipids play a pivotal role in the pathogenesis of respiratory virus infection. However, a direct comparison of the lipidomic profile of influenza virus and rhinovirus infections is lacking. In this study, we first compared the lipid profile of influenza virus and rhinovirus infection in a ...
2022-11-15 | MTBLS2352 | MetaboLights
UnknownPancreatic tuberculosis mimicking pancreatic carcinoma during anti-tuberculosis therapy: A case report.
Not available
S-EPMC4023313 | biostudies-literature
UnknownHepatocyte nuclear factor 4α induces a tendency of differentiation and activation of rat hepatic stellate cells.
Not available
S-EPMC4438019 | biostudies-literature
MetabolomicsFlavonoid Biosynthesis Is Likely More Susceptible to Elevation and Tree Age Than Other Branch Pathways Involved in Phenylpropanoid Biosynthesis in Ginkgo Leaves
Ginkgo leaves are always resources for flavonoids pharmaceutical industry. However, the effect of the elevation and tree age changes on flavonoid biosynthesis have not been detailly explored in Ginkgo leaves. In addition, whether these environmental pressures have similar effects on the biosynthesis...
2020-12-14 | MTBLS962 | MetaboLights
TranscriptomicsCombined miRNA and mRNA Sequencing Identifies Protective Transcriptional Signature of Enhanced PI3Kalpha Signaling in Cardiac Hypertrophy
A molecular and bioinformatic pipeline permitting comprehensive analysis and quantification of myocardial miRNA and mRNA expression with next-generation sequencing was developed and the impact of enhanced PI3Kalpha signaling on the myocardial transcriptome signature of pressure overload-induced path...
ORGANISM(S): Mus musculus 
2013-05-01 | E-GEOD-35350 | biostudies-arrayexpress
TranscriptomicsDeep RNA Sequencing Reveals Dynamic Regulation of Myocardial Noncoding RNA in Failing Human Heart and Remodeling with Mechanical Circulatory Support
Complete transcriptome profiling in human failing and non-failing control hearts using next-gen sequencing Poly-A selected RNA and small RNA sequencing carried out in 5 groups of samples: NF, ICM, NICM, ICM+LVAD, NICM+LVAD
ORGANISM(S): Homo sapiens 
2014-02-10 | E-GEOD-46224 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of initial stages of metanephric development in mouse and rat
In this study we identify molecules with highly restricted expression patterns during the initial stages of metanephric development, when the ureteric bud has entered the metanephric mesenchyme and initiated branching morphogenesis. Using the Affymetrix Mouse Genome 430 2.0 Array, we compare gene ex...
ORGANISM(S): Mus musculus 
2007-07-24 | E-GEOD-1983 | biostudies-arrayexpress
ProteomicsCanonical autophagy remains inactive in induced pluripotent stem cells and neuronal progenitor cells following DNA damage induced by BPDE or etoposide
(Macro-)Autophagy is a key cellular stress response mediating the recycling of long-lived or damaged proteins and organelles. In stem cells, autophagy is essential for the decision between quiescence, self-renewal and differentiation. We observed that induced pluripotent stem cells (iPSCs) and there...
ORGANISM(S): Homo sapiens (Human) 
2026-05-13 | PXD066480 | Pride
Autophagy  ipsc  npc  etoposide  bpde 
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