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To investigate the mechanisms underlying fluctuating IRE1α phosphorylation under chronic endoplasmic reticulum stress, we performed co-immunoprecipitation coupled with mass spectrometry (IP-MS) to identify IRE1α-interacting proteins. Protein complexes were analyzed by LC-MS/MS, followed by bioinform...
ORGANISM(S): Homo Sapiens 
2026-01-30 | PXD073899 |
Human glioma pathogenesis-related protein 1 (GLIPR1) and its mouse counterpart, Glipr1 are downregulated in prostate cancer (PCa) and other malignant cell lines, owing partly to methylation in the gene’s regulatory region. Loss of Glipr1 function predisposed mice to tumorigenesis. Restoration of GLI...
ORGANISM(S): Homo sapiens 
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