Sort   by:  
 Page size 
UnknownRandomized, Prospective Evaluation Comparing Intensity of Lymphodepletion Before Adoptive Transfer of Tumor-Infiltrating Lymphocytes for Patients With Metastatic Melanoma.
Not available
S-EPMC4981979 | biostudies-literature
TranscriptomicsEfficacy of retinoids in IKZF1-mutated BCR-ABL1 acute lymphoblastic leukemia
Alterations of IKZF1, encoding the lymphoid transcription factor IKAROS, are a hallmark of high risk acute lymphoblastic leukemia (ALL), however the role of IKZF1 alterations in ALL pathogenesis is poorly understood. Here we show that in mouse models of BCR-ABL1 leukemia, Ikzf1 and Arf alterations s...
ORGANISM(S): Mus musculus 
2015-09-04 | E-GEOD-68391 | biostudies-arrayexpress
ProteomicsCovalent inhibitor design confers activity against both GDP- and GTP-bound forms of KRAS G12C
The discovery of KRAS G12C inactive state inhibitors represents a significant advancement in the field of precision oncology. While inactive state inhibition shows promise in patients, SWII-binding inhibitors targeting both inactive and active states remain an underdeveloped therapeutic modality. H...
ORGANISM(S): Homo sapiens (Human) 
2025-11-04 | PXD062227 | Pride
TranscriptomicsPrevention of bone marrow cell apoptosis and regulation of hematopoiesis by type I IFNs during systemic responses to pneumocystis (PC) lung infection
IFrag-/- but not RAG-/- mice develop rapidly progressing bone marrow failure in response to PC lung infection. Changes contributing to accelerated bone marrow cell apoptosis in IFrag-/- mice appear to be initiated around day 7 post infection. To gain further insight into the mechanism underlying the...
ORGANISM(S): Mus musculus 
2012-02-20 | E-GEOD-27835 | biostudies-arrayexpress
TranscriptomicsOutcomes of Allogeneic Hematopoietic Cell Transplantation in Adults with fusions associated with Ph-like ALL
Allogenic hematopoietic cell transplantation (alloHCT) is a well-established curative modality for adults with high-risk ALL; yet large data describing alloHCT outcomes in Philadelphia (Ph)-like ALL is lacking. We retrospectively analyzed archived DNA samples from consecutive adults with B-cell Ph-n...
ORGANISM(S): Homo sapiens 
2022-08-01 | E-MTAB-11954 | biostudies-arrayexpress
TranscriptomicsIdentification of prognostic gene signatures in AML
Increased expression levels of miR-181 family members have been shown to be associated with favorable outcome in patients with cytogenetically normal acute myeloid leukemia. Here we show that increased expression of miR-181a and miR-181b is also significantly (P < .05; Cox regression) associated wit...
ORGANISM(S): Homo sapiens 
2012-04-03 | E-GEOD-30285 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of acteylcholine receptor immunization between RIIIS/J and B10.RIII mice
Comparison of acetylcholine receptor immunization between RIIIS/J and B10.RIII mice.
ORGANISM(S): Mus musculus 
2004-03-11 | E-MEXP-86 | biostudies-arrayexpress
TranscriptomicsFDB1_GM-CSFTyr577_Receptor_Mutant_Factorial_Time_Course_Study
To understand better the mechanisms controlling the balance between proliferation and and differentiation during myelopoiesis we have utilized teh bi-potent FDB1 myeloid cell line which differentiates to granulocytes and macrophages in response to GM-CSF and thus provides a dissectable model to anal...
ORGANISM(S): Mus musculus 
2010-12-07 | E-GEOD-25857 | biostudies-arrayexpress
UnknownRegional Practice Variation and Outcomes in the Standard Versus Accelerated Initiation of Renal Replacement Therapy in Acute Kidney Injury (STARRT-AKI) Trial: A Post Hoc Secondary Analysis.
Not available
S-EPMC10878545 | biostudies-literature
Sort   by:  
 Page size