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GenomicsCo-regulation of transcription factor binding and nucleosome occupancy through DNA features of mammalian enhancers
In mammalian cells transcription factors (TFs) preferentially bind sites contained in regions of high nucleosomal occupancy, as determined by nucleotide-dependent computational analysis. This observation suggests that nucleosomes may act as gatekeepers of TF binding sites. We hypothesized that in ma...
ORGANISM(S): Mus musculus 
2014-05-08 | E-GEOD-50762 | biostudies-arrayexpress
UnknownOptimization of Extraction Technology of Majun Mupakhi Ela and its Effect on Hydrocortisone-induced Kidney Yang Deficiency in Mice.
Not available
S-EPMC6420599 | biostudies-literature
TranscriptomicsPU.1 restricts adult hematopoietic stem cell proliferation via cell specific autoregulation
To guarantee blood supply throughout adult life hematopoietic stem cells (HSCs) need to carefully balance between self-renewing cell divisions and quiescence. Identification of genes controlling HSC self-renewal is of utmost importance given that HSCs are the only stem cells with broad clinical appl...
ORGANISM(S): Mus musculus 
2011-12-01 | E-GEOD-33031 | biostudies-arrayexpress
UnknownPharmacokinetics, Tissue Distribution and Excretion of a Novel Diuretic (PU-48) in Rats.
Not available
S-EPMC6160999 | biostudies-literature
ProteomicsA systemic view of microbial ecology in spontaneous fermentation of Chinese traditional pu-erh tea
To study the microbial functions, metaproteomes were extracted from 36 samples of fermented tea leaves and subjected to LC-MS/MS analyses. The MS/MS data were searched against the UniProt-protein database of the dominant microorganisms in the sample as identified by previous meta-barcoding analysis....
ORGANISM(S): Aspergillus Thermomyces Rasamsonia 
2019-01-03 | PXD012223 |
UnknownSustained PU.1 levels balance cell-cycle regulators to prevent exhaustion of adult hematopoietic stem cells.
Not available
S-EPMC3644723 | biostudies-literature
UnknownCharacterization of volatile metabolites in Pu-erh teas with different storage years by combining GC-E-Nose, GC-MS, and GC-IMS.
Not available
S-EPMC10314134 | biostudies-literature
UnknownEffects of home-based prescribed pulmonary exercise by patients with chronic obstructive pulmonary disease: study protocol for a randomized controlled trial.
Not available
S-EPMC6330445 | biostudies-literature
UnknownIntegrated Analysis of Chromatin and Transcriptomic Profiling Identifies PU.1 as a Core Regulatory Factor in Microglial Activation Induced by Chronic Cerebral Hypoperfusion.
Not available
S-EPMC11043206 | biostudies-literature
UnknownUnraveling the flavor formation process of mellow and thick-type ripened Pu-erh tea through non-targeted metabolomics and metagenomics.
Not available
S-EPMC12002954 | biostudies-literature
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