Sort   by:  
 Page size 
UnknownDirected evolution engineering to improve activity of glucose dehydrogenase by increasing pocket hydrophobicity.
Not available
S-EPMC9681798 | biostudies-literature
ProteomicsFascin Controls Metastatic Colonization and Mitochondrial Oxidative Phosphorylation by Remodeling Mitochondrial Actin Filaments/The mitochondrial deoxyguanosine kinase is required for the self-renewal of cancer stem-like cell in lung adenocarcinoma
Project 1: The deregulation of the actin cytoskeleton has been extensively studied in metastatic dissemination. However, the post-dissemination role of the actin cytoskeleton dysregulation is poorly understood. Here we report that fascin, an actin-bundling protein, promotes lung cancer metastatic co...
ORGANISM(S): Homo sapiens (Human) 
2019-09-12 | PXD014753 | Pride
Mitochondria Actin cytoskeleton Deoxyguanosine kinase Metastasis Fascin Lung cancer Stem-like cells 
MetabolomicsFSCN1 as a new druggable target in adrenocortical carcinoma

Adrenocortical carcinoma (ACC) is a rare endocrine malignancy with a high risk of relapse and metastatisation. The actin-bundling protein fascin (FSCN1) is overexpressed in aggressive ACC and represents a reliable prognostic indicator. FSCN1 has been shown to synergize with the Rho/Rac GEF VAV2 i...

2023-03-20 | MTBLS6402 | MetaboLights
ProteomicsEffects of FSCN1 inactivation on protein expression in human adrenocortical cancer cells
Adrenocortical carcinoma (ACC) is a rare endocrine malignancy with a high risk of relapse and metastatisation. The actin-bundling protein fascin (FSCN1) is overexpressed in aggressive ACC and represents a reliable prognostic indicator. FSCN1 has been shown to synergize with the Rho/Rac GEF VAV2 in e...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-11-18 | MSV000090738 | MassIVE
UnknownDrp1 splice variants regulate ovarian cancer mitochondrial dynamics and tumor progression
Not available
S-SCDT-10_1038-S44319-024-00232-4 | biostudies-other
Sort   by:  
 Page size