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MetabolomicsAirway Dysbiosis Accelerates Lung Function Decline in Chronic Obstructive Pulmonary Disease (Human UPLC-MS/MS assays)

Progressive decline in lung function is a hallmark of chronic obstructive pulmonary disease (COPD). Although airway dysbiosis occurs in COPD, whether it contributes to disease progression remains unknown. Here, through a longitudinal analysis on 181 COPD individuals from two large cohorts involvi...

2023-06-12 | MTBLS5423 | MetaboLights
MetabolomicsAirway Dysbiosis Accelerates Lung Function Decline in Chronic Obstructive Pulmonary Disease (Murine UPLC-MS/MS assays)

Progressive lung function decline is a hallmark of chronic obstructive pulmonary disease (COPD). Airway dysbiosis occurs in COPD, but whether it contributes to disease progression remains unknown. Here we showed, through a longitudinal analysis on two cohorts involving four UK centers, that basel...

2023-06-12 | MTBLS6894 | MetaboLights
ProteomicsProteomics and metabonomics analyses of Covid-19 complications in patients with pulmonary fibrosis
Pulmonary fibrosis is a devastating disease, and the pathogenesis of this disease is not completely clear. Here, the medical records of 85 Covid-19 cases were collected, among which fibrosis and progression of fibrosis were analyzed in detail. Next, data independent acquisition (DIA) quantification ...
ORGANISM(S): Homo Sapiens 
2021-02-22 | PXD024311 |
TranscriptomicsOptimized siRNAs with a minimal off-target effect facilitate the screening of essential genes in cancer cells
siRNAs with dN are a promising and easy approach to characterize essential genes by minimizing the off-target effect in cancer cells. mRNA profiles of HCT 116 cells after the transfection of siRNAs or blank control by deep sequencing, using HiSeq 2000
ORGANISM(S): Homo sapiens 
2015-07-01 | E-GEOD-62968 | biostudies-arrayexpress
UnknownEfficacy and Tolerability of First-Line Cetuximab Plus Leucovorin, Fluorouracil, and Oxaliplatin (FOLFOX-4) Versus FOLFOX-4 in Patients With RAS Wild-Type Metastatic Colorectal Cancer: The Open-Label, Randomized, Phase III TAILOR Trial.
Not available
S-EPMC6324088 | biostudies-literature
ProteomicsCirculating proteome profiling of Guangzhou Nutrition and Health Study
Guangzhou Nutrition and Health Study was a community-based cohort study in Guangzhou, China.
ORGANISM(S): Homo Sapiens 
2023-01-03 | PXD039231 |
ProteomicsCirculating proteome profiling of Westlake Precision Birth Cohort
Westlake Precision Birth Cohort (WEBIRTH) consists of gestational women living in Hangzhou, China.
ORGANISM(S): Homo Sapiens 
2022-11-22 | PXD038253 |
ProteomicsGNHS proteome SWATH data datatat
Here, we explored the feasibility to use a protein-based machine learning model for risk prediction of MetS in a prospective cohort.
ORGANISM(S): Homo Sapiens 
2023-03-11 | PXD039236 |
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