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MetabolomicsAirway Dysbiosis Accelerates Lung Function Decline in Chronic Obstructive Pulmonary Disease (Human UPLC-MS/MS assays)

Progressive decline in lung function is a hallmark of chronic obstructive pulmonary disease (COPD). Although airway dysbiosis occurs in COPD, whether it contributes to disease progression remains unknown. Here, through a longitudinal analysis on 181 COPD individuals from two large cohorts involvi...

2023-06-12 | MTBLS5423 | MetaboLights
MetabolomicsAirway Dysbiosis Accelerates Lung Function Decline in Chronic Obstructive Pulmonary Disease (Murine UPLC-MS/MS assays)

Progressive lung function decline is a hallmark of chronic obstructive pulmonary disease (COPD). Airway dysbiosis occurs in COPD, but whether it contributes to disease progression remains unknown. Here we showed, through a longitudinal analysis on two cohorts involving four UK centers, that basel...

2023-06-12 | MTBLS6894 | MetaboLights
ProteomicsProteomics and metabonomics analyses of Covid-19 complications in patients with pulmonary fibrosis
Pulmonary fibrosis is a devastating disease, and the pathogenesis of this disease is not completely clear. Here, the medical records of 85 Covid-19 cases were collected, among which fibrosis and progression of fibrosis were analyzed in detail. Next, data independent acquisition (DIA) quantification ...
ORGANISM(S): Homo Sapiens 
2021-02-22 | PXD024311 |
TranscriptomicsOptimized siRNAs with a minimal off-target effect facilitate the screening of essential genes in cancer cells
siRNAs with dN are a promising and easy approach to characterize essential genes by minimizing the off-target effect in cancer cells. mRNA profiles of HCT 116 cells after the transfection of siRNAs or blank control by deep sequencing, using HiSeq 2000
ORGANISM(S): Homo sapiens 
2015-07-01 | E-GEOD-62968 | biostudies-arrayexpress
UnknownEfficacy and Tolerability of First-Line Cetuximab Plus Leucovorin, Fluorouracil, and Oxaliplatin (FOLFOX-4) Versus FOLFOX-4 in Patients With RAS Wild-Type Metastatic Colorectal Cancer: The Open-Label, Randomized, Phase III TAILOR Trial.
Not available
S-EPMC6324088 | biostudies-literature
ProteomicsRNA-Binding Motif protein 6 is a candidate serum biomarker for pancreatic cancer
Early diagnosis is crucial to improve outcomes for pancreatic cancer (PC) patients, however the lack of specific and validated biomarkers for the disease remains challenging. In this study, we analyzed the serum proteome of 12 PC patients and 76 healthy controls (HC), using magnetic bead-based weak ...
ORGANISM(S): Homo Sapiens 
2019-04-25 | PXD013626 |
ProteomicsCirculating proteome profiling of Guangzhou Nutrition and Health Study
Guangzhou Nutrition and Health Study was a community-based cohort study in Guangzhou, China.
ORGANISM(S): Homo Sapiens 
2023-01-03 | PXD039231 |
ProteomicsGNHS proteome SWATH data datatat
Here, we explored the feasibility to use a protein-based machine learning model for risk prediction of MetS in a prospective cohort.
ORGANISM(S): Homo Sapiens 
2023-03-11 | PXD039236 |
ProteomicsCirculating proteome profiling of Westlake Precision Birth Cohort
Westlake Precision Birth Cohort (WEBIRTH) consists of gestational women living in Hangzhou, China.
ORGANISM(S): Homo Sapiens 
2022-11-22 | PXD038253 |
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