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Transcriptomicsm6A RNA Methylation Is Regulated by MicroRNAs and Promotes Reprogramming to Pluripotency
N6-methyladenosine (m6A) has been recently identified as a conserved epitranscriptomic modification of eukaryotic mRNAs, but its features, regulatory mechanisms, and functions in cell reprogramming are largely unknown. Here, we report m6A modification profiles in the mRNA transcriptomes of four cell...
ORGANISM(S): Mus musculus 
2015-03-10 | E-GEOD-52125 | biostudies-arrayexpress
UnknownThe lncRNA Firre anchors the inactive X chromosome to the nucleolus by binding CTCF and maintains H3K27me3 methylation.
Not available
S-EPMC4391730 | biostudies-literature
ProteomicsPFKM promotes the survival of GBM cells under glucose deprivation
PFKM is the second rate-limiting step of glycolysis, catalyzing the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate. Here we show, using an orthotopic xenograft glioma mouse model, that PFKM is deubiquitinated and translocated into nucleus upon glucose deficiency, thereby activa...
ORGANISM(S): Homo Sapiens 
2026-02-15 | PXD074827 |
ProteomicsInteraction partners with NOP2/Sun RNA methyltransferase 2 (NSUN2) in gallbladder carcinoma
Proteins interacting with NSUN2 in gallbladder carcinoma (NOZ cell line)
ORGANISM(S): Homo Sapiens 
2019-03-20 | PXD013152 |
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