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MetabolomicsA metabolome atlas of mouse brain on the global metabolic signature dynamics following short-term fasting
Calorie restriction (CR) or a fasting regimen is considered one of the most potent non-pharmacological interventions to prevent chronic metabolic disorders, ameliorate autoimmune diseases, and attenuate aging. Despite efforts, the mechanisms by which CR improves health, particularly brain health, ar...
2025-07-31 | MTBLS8006 | MetaboLights
Proteomicsthe Effect of Fatty Acids in Hepatic Insulin resistance-part2
Monounsaturated fatty acid (MUFA) oleic acid (OA) has been reported to reverse saturated fatty acid palmitic acid (PA)-induced hepatic insulin resistance (IR). However, the detailed molecular mechanism remains elusive. In addition, previous research also showed that -3 polyunsaturated fatty acid (PU...
ORGANISM(S): Homo sapiens (Human) 
2019-07-11 | PXD012066 | Pride
Human  free fatty acids  insulin resistance  quantitative proteomics  calcium  atp. 
ProteomicsThe Effect of Fatty Acids in Hepatic Insulin Resistance - Part 1
Monounsaturated fatty acid (MUFA) oleic acid (OA) has been reported to restore saturated fatty acid palmitic acid (PA)-induced hepatic insulin resistance (IR). However, the detailed molecular mechanism remains elusive. In addition, -3 polyunsaturated fatty acid (PUFA) such as Eicosapentaenoic acid (...
ORGANISM(S): Homo sapiens (Human) 
2019-07-11 | PXD012065 | Pride
Fatty acids  insulin resistance  pa  epa 
UnknownEfficacy and Safety of Platinum-Based Chemotherapy for Ovarian Cancer During Pregnancy: A Systematic Review and Meta-Analysis.
Not available
S-EPMC9098723 | biostudies-literature
ProteomicsGrass carp SERPINA1 CoIP with hepatopancreas mass spectrometry analysis
SERPINA1, a member of the serine protease inhibitor family, plays a role in viral infection and inflammation by regulating the activities of serine and cysteine proteases. To further investigate the antiviral role SERPINA1 played in GCRV (Grass carp Reovirus) infection, a polyclonal antibody of SERP...
ORGANISM(S): Ctenopharyngodon idella 
2022-08-31 | PXD036356 | Pride
Serpina1 Grass carp Coip/ms Hepatopancreas 
TranscriptomicsGene expression associated with lentiviral expression of PRAME in normal hematopoietic progenitors.
To identify gene expression that distinguishes hematopoietic cells that express PRAME from those that do not, normal CD34+ cells with forced PRAME expression were compared to cells without PRAME expression in culture over time (days 4, 7, 14) using Affymetrix HU-133A microarrays Normal CD34+ progen...
ORGANISM(S): Homo sapiens 
2009-10-31 | E-GEOD-17100 | biostudies-arrayexpress
ProteomicsProteomic analysis of patients with advanced triple-negative breast cancer
In the later-line setting or for patients with PD-L1-negative tumors, immunotherapy-based regimens remain ineffective against advanced triple-negative breast cancer (TNBC). In this multicentered phase II trial (NCT04303741), 46 patients with pretreated advanced TNBC were enrolled to receive camreliz...
ORGANISM(S): Homo Sapiens 
2022-05-04 | PXD033655 |
Proteomicsthe proteomics of IGFBP6 in endothelial cells (HUVECs)
To unravel the direct mechanism of the anti-inflammatory effects of IGFBP6 in ECs, we analysed HUVECs treated with either adenovirus-Flag-IGFBP6 (Ad-IGFBP6) or control adenovirus (Ad-NC). We precipitated IGFBP6 from overexpressed ECs followed by mass spectrometry.
ORGANISM(S): Homo Sapiens 
PXD052204 |
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