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We employ Mass spectrum to investigate proteome of Pum1-Knockout, Pum2-Knockout and WT conditions in human colorectal cancer cell line Hct116. Overall design: In order to investigate whether Pum1 and Pum2 regulate their targets at their protein levels, we used Pum1-Knockout, Pum2-Knockout and WT Hct...
ORGANISM(S): Homo Sapiens 
2021-07-23 | PXD027513 |
Reader proteins play significant roles in cell signaling from site-specific lysine methylation, but the progress of new reader investigations is rather slow. Photoreactive crosslinkers enable reader identifications, but it requires laborious chemical synthesis for optimization of the photoreactive g...
ORGANISM(S): Homo Sapiens 
2024-02-04 | PXD049149 |
The project aims to investigate the molecular mechanisms of aging by analyzing protein expression and modifications across various tissues in multiple organisms. Using advanced mass spectrometry, the project will collect and compare proteomic profiles from different organs at various ages. By identi...
ORGANISM(S): Mus Musculus 
2025-03-18 | PXD061948 |
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