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MetabolomicsIntegrated omics analysis reveals the alteration of gut microbiota and fecal metabolites in Cervus elaphus kansuensis
The gut microbiota is the largest and most complex microecosystem in animals. It is influenced by the host's dietary habits and living environment, and its composition and diversity play irreplaceable roles in animal nutrient metabolism, immunity, and adaptation to the environment. Although the gut ...
2024-08-08 | MTBLS6121 | MetaboLights
MetabolomicsThe lipid-metabolism enzyme ECI2 reduces neutrophil extracellular traps formation for colorectal cancer suppression
Abnormalities in ether lipid metabolism as well as the formation of neutrophil extracellular traps have recently been recognized as detrimental factors affecting tumorigenesis and progression. However, the role of abnormal ether lipid metabolism in colorectal cancer (CRC) evolution has not been repo...
2024-10-01 | MTBLS10323 | MetaboLights
UnknownTranscriptome analysis of Valsa mali reveals its response mechanism to the biocontrol actinomycete Saccharothrix yanglingensis Hhs.015.
Not available
S-EPMC6106759 | biostudies-literature
TranscriptomicsRNA-seq of roots of Schrenkiella parvula seedlings treated with 0mM or 175mM NaCl for 0 h, 3 h, 24 h and 48 h.
The purpose of the experiments is to understand transcriptional reprogramming in roots of halophyte Schrenkiella parvula (S. parvula) that may contribute to its high salt tolerance. Root materials were harvested from S. parvula seedlings grown on agar plates with ½ strength Murashige-Skoog (½MS) med...
2023-02-18 | E-MTAB-12424 | biostudies-arrayexpress
MetabolomicsCombined analysis of transcriptome and metabolome of large size triploid rainbow trout in different seasons
Seasonal temperature variation poses a major physiological challenge for cold-water aquaculture species, yet the molecular mechanisms underlying seasonal adaptation in large-sized triploid rainbow trout (Oncorhynchus mykiss) remain largely unexplored. Here, we integrated liver transcriptomics and LC...
2026-07-11 | MTBLS15014 | MetaboLights
Transcriptomicswenyan
Kashin-Beck disease (KBD) is an endemic and chronic osteochondropathy with unknown etiology. The disease mostly occurs in children between the ages of 3 and 13 in a diagonal belt-like area ranging from Northeast to Southwest China. We carried out this microarray analysis to investigate the differenc...
ORGANISM(S): Homo sapiens 
2014-08-30 | E-MTAB-2494 | biostudies-arrayexpress
ProteomicsDe novo pyrimidine biosynthetic complexes support cancer cell proliferation and ferroptosis defense
De novo pyrimidine biosynthesis is achieved by cytosolic enzymes, CAD and UMPS, and mitochondrial DHODH. However, how these enzymes are orchestrated remains enigmatical. Here, we show that cytosolic aspartate-producing GOT1 clusters with CAD and UMPS. This cytosolic cluster then connects with DHODH,...
ORGANISM(S): Homo Sapiens 
2023-03-22 | PXD041017 |
TranscriptomicsHuman Peripheral blood mononuclear cells (PBMCs): Control vs. Kashin-Beck Disease
Objective:To identify an accurate blood-based gene signature for early detection of Kashin-Beck disease (KBD). Methods: Gene expression analysis was conducted of peripheral blood samples from 100 patients with KBD and 100 controls randomly chosen from two KBD-endemic areas Two-condition experiment, ...
ORGANISM(S): Homo sapiens 
2014-07-16 | E-GEOD-59446 | biostudies-arrayexpress
UnknownOptimal Thromboprophylaxis in Elderly Chinese Patients with Atrial Fibrillation (ChiOTEAF) registry: protocol for a prospective, observational nationwide cohort study.
Not available
S-EPMC5942423 | biostudies-literature
UnknownPatterns of comorbidities, clinical course, and impact of the ABC Pathway for Integrated Care in patients with atrial fibrillation: a report from the prospective Optimal Thromboprophylaxis in Elderly Chinese Patients with Atrial Fibrillation (ChiOTEAF) Registry.
Not available
S-EPMC12587286 | biostudies-literature
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