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TranscriptomicsA gp130-induced Src/Yes-YAP Cascade Links Inflammation to Regeneration in the Mammalian Intestine
gp130Act cDNA was PCR-amplified and inserted into a plasmid containing the 12.4-kb Villin promoter. The 15.7-kb expression cassette was excised by PmeI digestion, purified, and injected into fertilized C57BL/6 oocytes to obtain founder mice, two of which transmitted the gp130Act transgene. Small int...
ORGANISM(S): Mus musculus 
2015-02-21 | E-MTAB-2400 | biostudies-arrayexpress
UnknownBlockade of Fibroblast YAP Attenuates Cardiac Fibrosis and Dysfunction Through MRTF-A Inhibition.
Not available
S-EPMC7524792 | biostudies-literature
UnknownA miR-375/YAP axis regulates neuroendocrine differentiation and tumorigenesis in lung carcinoid cells.
Not available
S-EPMC8129150 | biostudies-literature
ProteomicsHBV remodels PP2A complexes to rewire kinase signaling in hepatocellular carcinoma
Hepatitis B virus (HBV) infection promotes liver cancer initiation by inducing inflammation and cellular stress, but its impact in established tumors is not well understood. We used affinity purification mass spectrometry to comprehensively map a network of 145 physical interactions between HBV and ...
ORGANISM(S): Homo sapiens (Human) 
2024-11-23 | PXD055366 | Pride
Hepatitis b Pp2a Signaling Hepatocellular carcinoma 
ProteomicsHDAC inhibition enhances the in vivo efficacy of MEK inhibitor therapy in uveal melanoma
Purpose: The clinical use of MEK inhibitors in uveal melanoma is limited by the rapid acquisition of resistance. The current study has used multi-omics approaches and drug screens to identify the pan-HDAC inhibitor panobinostat as an effective strategy to limit MEK inhibitor resistance. Experimental...
ORGANISM(S): Homo sapiens (Human) 
2020-05-26 | PXD013988 | Pride
Uveal melanoma Hdac Abpp 
UnknownCervical Cancer Incidence in the US-Affiliated Pacific Islands.
Not available
S-EPMC11393751 | biostudies-literature
UnknownCancer cell adaptation to hypoxia involves a HIF-GPRC5A-YAP axis
Not available
S-SCDT-EMM-2017-08699 | biostudies-other
UnknownBuilding Capacity for Cervical Cancer Prevention in U.S.-Affiliated Pacific Islands: The Pacific Against Cervical Cancer Project.
Not available
S-EPMC11995255 | biostudies-literature
UnknownThe Hippo effector TAZ (WWTR1) transforms myoblasts and TAZ abundance is associated with reduced survival in embryonal rhabdomyosarcoma.
Not available
S-EPMC4995731 | biostudies-literature
UnknownBreast cancer incidence and stage at diagnosis in the six US-Affiliated Pacific Islands.
Not available
S-EPMC11402563 | biostudies-literature
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