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ProteomicsProteasome-dependent truncation of the negative heterochromatin regulator Epe1 mediates antifungal resistance.
Epe1 histone demethylase restricts H3K9-methylation-dependent heterochromatin, preventing it from spreading over, and silencing, gene-containing regions in fission yeast. External stress induces an adaptive response allowing heterochromatin island formation that confers resistance on surviving wild-...
ORGANISM(S): Schizosaccharomyces pombe 927 
2022-10-13 | PXD030205 | Pride
Fission yeast Epe1 Shotgun proteomics. Anti-fungal resistance H3k9-methylation Proteasome Heterochromatin 
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