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TranscriptomicsDissecting physiological and transcriptional responses of nitric oxide to drought stress by increasing in vivo nitric oxide content in Arabidopsis
Nitric oxide (NO) is involved in all major environmental stresses. However, most of these understandings were mainly based on pharmacological study using NO modulator compounds. Recently, our studies together with others provided a new class of plant experimental system with specific in vivo NO rele...
ORGANISM(S): Arabidopsis thaliana 
2014-06-03 | E-GEOD-48474 | biostudies-arrayexpress
ProteomicsTau accumulation induces spatial memory deficit via disrupting medial septum-hippocampus cholinergic pathway
By precisely dissected MS for proteomics, we found that donepezil remarkably restored (at high dose), even elevated (at low dose) the level of vacuolar protein sorting-associated protein 37D (VP37D), an autophagy-related protein, in hTauMS mice.
ORGANISM(S): Mus musculus (Mouse) 
2021-09-09 | PXD023297 | Pride
Mouse Medial septum Hippocampus Alzheimer’s disease Cholinergic neuron Tau accumulation 
Proteomics5HT - Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3
we provide evidence for a new class of histone posttranslational modification (PTM): serotonylation.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-12-04 | MSV000093567 | MassIVE
ProteomicsMass spectrometry-based protein interactome and phosphoproteomics data upon NRDE2 overexpression
The HEK293T cells transiently expressing Flag-tagged empty vector or Flag-NRDE2-WT were lysed in NETN buffer (10 mM Tris-HCl [pH 8.0], 100 mM NaCl, 1 mM EDTA, and 0.5% NP-40) and immunoprecipitated with anti-Flag M2 agarose (M8823; Sigma-Aldrich, MO, USA). After washing four times with the high stri...
ORGANISM(S): Homo Sapiens 
2024-03-31 | PXD051117 |
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