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ProteomicsLong-Term Hepatitis B Virus Infection Induces Cytopathic Effects in Primary Human Hepatocytes and Can be Partially Reversed by Antiviral Therapy
Global temporal quantitative proteomic and transcriptomic analysis using long-term hepatitis B virus (HBV)-infected primary human hepatocytes uncovered extensive remodeling of host proteome and transcriptome, and revealed cytopathic effects of long-term viral replication. Metabolic-, complement-, cy...
ORGANISM(S): Homo Sapiens 
2021-08-31 | PXD028190 |
ProteomicsLong-Term Hepatitis B Virus Infection Induces Cytopathic Effects in Primary Human Hepatocytes, and Can be Partially Reversed by Antiviral Therapy
Proteomics analysis was then applied to identify genes or pathways that could be rescued by RNAi.
ORGANISM(S): Homo Sapiens 
2022-02-01 | PXD031397 |
ProteomicsIdentification of TRADD phosphorylation sites
We re-introduced Flag-mTRADD into Tradd-/- MEFs, and identified the phosphorylation sites of TRADD which were induced by TNF and inhibited by TAK1 inhibitor 5Z7 using mass spectrometry. We found that TAK1 could mediate the phosphorylation of multiple sites in TRADD upon TNF stimulation. We next perf...
ORGANISM(S): Homo Sapiens 
2024-10-05 | PXD056588 |
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