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UnknownEvolutionary Trend Analysis of Research on 5-ALA Delivery and Theranostic Applications Based on a Scientometrics Study.
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S-EPMC9320574 | biostudies-literature
ProteomicsCyclic immonium ion of lactyllysine reveals widespread lactylation in the human proteome
Here we employed a non-enzymatic chemical labeling approach to introduce lactylation on lysine residues of model peptides and proteins. Tandem MS acquisition of lactylated peptide carriers on different MS platforms unequivocally led us to note an intense peak corresponding to the “cyclic” immonium ...
ORGANISM(S): Homo Sapiens 
2021-09-15 | PXD028488 |
ProteomicsSimultaneous profiling of phosphorylation and S-nitrosylation during maize seed germination
We developed a phosphate-affinity tag-switch (PAT-switch) proteomics workflow enabling simultaneous, site-specific profiling of phosphorylation and S-nitrosylation during maize seed germination.
ORGANISM(S): Zea Mays 
2026-01-21 | PXD073327 |
ProteomicsCanagliflozin ameliorates progestin resistance by suppressing RARβ/CRABP2 signaling in TRβ knockout endometrial cancer cells
THRB-knockout RL95-2 (THRB(-/-)/RL95-2) cells were constructed to investigate progestin resistance mechanisms. Cell proliferation and apoptosis were assessed in RL95-2 and THRB(-/-)/RL95-2 cells treated with canagliflozin (CANA), medroxyprogesterone acetate (MPA), or their combination using CCK-8, E...
ORGANISM(S): Homo Sapiens 
2025-02-07 | PXD060591 |
ProteomicsCleavage of CAD by caspase-3 determines the cancer cell fate during chemotherapy
Metabolic heterogeneity resulting from the intrinsic heterogeneity of human tumors has been shown to cause a myriad of adverse outcomes of tumor therapy, including resistance to chemotherapy, but the mechanisms inside remain largely unknown. Here, we found that the de novo pyrimidine synthesis pathw...
ORGANISM(S): Homo Sapiens 
2025-01-01 | PXD059365 |
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