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ProteomicsProtein Lactylation modification and Proteomics Features in Cirrhosis Patients after MSCs Treatment.
Mesenchymal stem cell (MSC) therapy improves liver function in patients with liver cirrhosis. However, the therapeutic mechanism underlying MSC therapy remains unclear. Therefore, this study aimed to elucidate the therapeutic mechanism underlying MSC therapy by analyzing changes in the modification ...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD037530 | Pride
Liver cirrhosis  mesenchymal stem cell  cell therapy  lactylation modification  proteomics analysis. 
UnknownA SIP1 gene of Trihelix family, SlGT-33, promotes chilling tolerance and fruits set under prolonged cold stress in tomatoes.
Not available
S-EPMC12522792 | biostudies-literature
TranscriptomicsIntegration of Hi-C and ChIP-seq data reveals distinct types of chromatin hubs
We have analyzed publicly available K562 Hi-C data, which enables genome-wide unbiased capturing of chromatin interactions, using a Mixture Poisson Regression Model to define a highly specific set of interacting genomic regions. We integrated multiple ENCODE Consortium resources with the Hi-C data, ...
ORGANISM(S): Homo sapiens 
2012-06-30 | E-GEOD-32213 | biostudies-arrayexpress
GenomicsRedefinition of Human Androgen Responsive Elements [FOX_ChIP_exo]
The androgen receptor (AR) mediates the action of androgens by binding to androgen-responsive elements (AREs) and subsequently regulating target genes involved in prostate carcinogenesis. The precise locations, true nature, and functional roles of AREs in human prostate cancer are still unknown. Her...
ORGANISM(S): Homo sapiens 
2015-01-01 | E-GEOD-43678 | biostudies-arrayexpress
GenomicsRedefinition of Human Androgen Responsive Elements [MNase-Seq, ChIP_seq]
The androgen receptor (AR) mediates the action of androgens by binding to androgen-responsive elements (AREs) and subsequently regulating target genes involved in prostate carcinogenesis. The precise locations, true nature, and functional roles of AREs in human prostate cancer are still unknown. Her...
ORGANISM(S): Homo sapiens 
2015-01-01 | E-GEOD-43720 | biostudies-arrayexpress
GenomicsLigand-dependent genomic function of glucocorticoid receptor in triple-negative breast cancer
Glucocorticoids (GC) have been widely used as coadjuvants in the treatment of solid tumors, but GC treatment may be associated with poor pharmacotherapeutic response and/or prognosis. The genomic action of GC in these tumors is largely unknown. Here we find that dexamethasone (Dex, a synthetic GC) r...
ORGANISM(S): Homo sapiens 
2015-09-18 | E-GEOD-56022 | biostudies-arrayexpress
GenomicsMeDIP sequencing of Ovis aries
We have completed the high quality reference genome for domestic sheep (Oar v3.1). Early-stage Illumina GA sequence platform sequenced less reads in high GC content regions than in other regions. To read through higher GC content regions, we generated 2 Gb MeDIP-seq data for filling gaps in sheep re...
ORGANISM(S): Ovis aries 
2014-06-06 | E-GEOD-56644 | biostudies-arrayexpress
Genomicsena-DATASET-DTU-22-02-2017-08:21:35:017-10 - samples
Variants and genotypes called in 50 danish parent-offspring trios from 80x Illumina sequencing data using BayesTyper. Data was produced using different insert size libraries of the sizes 180, 500, 800, 2000, 5000, 10000 and 20000 bp. The sample IDs for the fathers and mothers are TrioID-01 and TrioI...
EGAD00001003188 | EGA
UnknownHuang Gan Formula Alleviates Systemic Inflammation and Uremia in Adenine-Induced Chronic Kidney Disease Rats May Associate with Modification of Gut Microbiota and Colonic Microenvironment.
Not available
S-EPMC10777866 | biostudies-literature
Genomicsena-DATASET-DTU-19-07-2017-19:09:46:884-206 - samples
The MHC vcf call set was generated using a modified AsmVar and BayesTyper pipeline. In contrast to the original pipeline, where variant calling is performed using alignment of collapsed assemblies to a reference genome, the MHC call set was produced using alignment of phased MHC haplotypes. Two iter...
EGAD00001003455 | EGA
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