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MetabolomicsDeep functional analysis of synII, a 770 kb synthetic yeast chromosome
Here we report the design, construction and characterization of a 770 Kb synthetic yeast chromosome II (synII). With the UPLC-MS method, we demonstrated synII maintains a nearly wild-type phenotype and fitness despite hundreds of designer editing to it. Our phenomics, transcriptomics, proteomics dat...
2016-10-13 | MTBLS296 | MetaboLights
MetabolomicsA next-generation yeast chassis: comprehensive characterization of a robust fast-growing Saccharomyces cerevisiae

Robust and efficient hosts are necessary to facilitate advances in biotechnology. We unveil Saccharomyces cerevisiae strain XP as a promising new microbial chassis owing to its high growth rate and robustness. This strain has a doubling time of 48.2 min, which is 12.8 min faster than the...

2024-09-26 | MTBLS7328 | MetaboLights
TranscriptomicsAlpha-factor treatment of Saccharomyces cerevisiae
We measured the response of S. cerevisiae to arrest in the presence of alpha factor. These were collected in support of a related DNaseI-sequencing study. Keywords: Alpha-factor arrest S.cerevisiae R276 (MATa ura3Δ0 leu2Δ0 his3Δ1 met15Δ0 bar1Δ::KanMX) (C. Boone, University of Toronto; S288c backgro...
ORGANISM(S): Saccharomyces cerevisiae 
2008-12-01 | E-GEOD-11412 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis comparing yeast Eco1 mutant W216G to mutants of FOB1 and RAD61
Eco1 is an acetyltransferase subunit of the cohesin complex and acts during DNA replication to establish cohesion between sister chromatids. However, cohesin has additional functions in gene expression, DNA damage repair, and higher-order organization of chromosomes. The eco1 mutant W216G disrupts a...
ORGANISM(S): Saccharomyces cerevisiae 
2014-04-03 | E-GEOD-54741 | biostudies-arrayexpress
GenomicsPING 2.0: An R/Bioconductor package for nucleosome positioning using next-generation sequencing data
MNase-Seq and ChIP-Seq have evolved as popular techniques to study chromatin and histone modification. Although many tools have been developed to identify enriched regions, software tools for nucleosome positioning are still limited. We introduce a flexible and powerful open-source R package, PING 2...
ORGANISM(S): Saccharomyces cerevisiae 
2013-07-11 | E-GEOD-47073 | biostudies-arrayexpress
ProteomicsYeast glycoproteome - pGlyco 2
Precise and large-scale characterization of glycoproteome is critical for understanding the biological functions of glycoproteins. Due to the complexity of glycosylation, the overall throughput, data quality and accessibility of site-specific glycosylation analysis are overwhelmingly lower than thos...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2017-08-15 | PXD005565 | Pride
Yeast glycoproteome 
TranscriptomicsBackground analysis using yeast RNA on the Mouse 430 2.0 array
We hybridized yeast RNA to the mouse 430 2.0 array to estimate the background binding for each probe.
ORGANISM(S): Saccharomyces cerevisiae Mus musculus 
2011-01-01 | GSE22975 | GEO
TranscriptomicsBackground analysis using yeast RNA on the U133 plus 2.0 array
We used yeast RNA to estimate background binding for each probe on the human U133 plus 2.0 array.
ORGANISM(S): Saccharomyces cerevisiae Homo sapiens 
2011-01-01 | GSE22974 | GEO
TranscriptomicsTranscription profiling of lager brewing yeast strain during industrial propagation and fermentation
Commercial brewing yeast strains are exposed to a number of potential stresses including oxidative stress. The aim of this investigation was to measure the physiological and transcriptional changes of yeast cells during full-scale industrial brewing processes with a view to determining the environme...
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-16 | E-GEOD-9423 | biostudies-arrayexpress
TranscriptomicsWhole Genome Analysis of the Heat Stress Response in Commercial Baker's Yeast (Saccharomyces cerevisiae) with Comparative Statistical Approaches
Environmental conditions are quite effective during propagation and industrial application of Baker’s yeast (Saccharomyces cerevisiae). The change of temperature is one of the most important conditions which affects the dough-leaving capacity of yeast cells. Accordingly, heat changes play an essential...
ORGANISM(S): Saccharomyces cerevisiae S288c 
2017-01-30 | E-MTAB-3459 | biostudies-arrayexpress
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