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MetabolomicsA next-generation yeast chassis: comprehensive characterization of a robust fast-growing Saccharomyces cerevisiae

Robust and efficient hosts are necessary to facilitate advances in biotechnology. We unveil Saccharomyces cerevisiae strain XP as a promising new microbial chassis owing to its high growth rate and robustness. This strain has a doubling time of 48.2 min, which is 12.8 min faster than the...

2024-09-26 | MTBLS7328 | MetaboLights
MetabolomicsModel-guided development of evolutionarily stable yeast chassis for dicarboxylic acids production

Chassis strain suitable for producing multiple compounds is a central concept in synthetic biology. Design of a chassis using computational, first-principle, models is particularly attractive due to the predictability and control it offers, including against phenotype reversal due to adaptive mut...

2021-07-19 | MTBLS2007 | MetaboLights
ProteomicsAbsolute Quantification of Yeast Proteins Using Synthetic Peptide Standards and TMT labeling
The absolute protein amounts for the selected yeast ribosomal proteins (RPs) were determined using the standard peptides and TMT labelling. The range of the standard tryptic peptides were selected and synthesized based on the preliminary data-dependent experiments. The synthetic peptides were mixed ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2020-03-13 | PXD015025 | Pride
Tmt Yeast Tandem mass tag Standard peptides Saccharomyces cerevisiae Absolute quantification Synthetic peptides Orbitrap fusion 
TranscriptomicsRNA sequencing of pheromone stimulated and unstimulated MATa and MATM-NM-1 Saccharomyces cerevisiae
Haploid budding yeast has two mating types, defined by the alleles of the MAT locus, MATa and MATM-NM-1. Mating occurs when two haploid cells of opposite mating types signal to each other using reciprocal pheromones and receptors, polarize and grow towards each other, and eventually fuse to form a s...
ORGANISM(S): Saccharomyces cerevisiae 
2014-01-07 | E-GEOD-49372 | biostudies-arrayexpress
UnknownPOMBOX: A Fission Yeast Cloning Toolkit for Molecular and Synthetic Biology.
Not available
S-EPMC10877588 | biostudies-literature
UnknownCompacting a synthetic yeast chromosome arm.
Not available
S-EPMC7780613 | biostudies-literature
UnknownHigh-throughput yeast engineering in biofoundries: towards autonomous and scalable synthetic biology.
Not available
S-EPMC12927428 | biostudies-literature
UnknownYeast synthetic biology platform generates novel chemical structures as scaffolds for drug discovery.
Not available
S-EPMC4046787 | biostudies-literature
TranscriptomicsSynthetic circuit identifies subpopulations with sustained memory of DNA damage
Differential responses to stimuli can affect how cells succumb to disease. In yeast, DNA damage can create heterogeneous responses. To delineate how a response contributes to a cell's future behavior, we constructed a transcription-based memory circuit that detects DNA repair to isolate subpopulatio...
ORGANISM(S): Saccharomyces cerevisiae 
2012-03-02 | E-GEOD-36210 | biostudies-arrayexpress
UnknownThe Synthetic Genome Summer Course.
Not available
S-EPMC7445779 | biostudies-literature
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