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UnknownAssociation of Vitamin D Levels With Outcome in Patients With Melanoma After Adjustment For C-Reactive Protein.
Not available
S-EPMC4966337 | biostudies-literature
ProteomicsO-GlcNAcylation promotes Palbociclib resistance in breast cancer by regulating MITF nuclear translocation
Cyclin-dependent kinases 4 and 6 (CDK4/6) are essential drivers of the cell cycle and are also critical for the initiation and progression of diverse malignancies. Pharmacological inhibitors targeting CDK4/6 have demonstrated significant activity against various tumor types such as breast cancer. Ho...
ORGANISM(S): Homo sapiens (Human) 
2024-05-30 | PXD042763 | Pride
O-glcnacylation Mitf Palbociclib 
ProteomicsO-GlcNAcylation promotes Palbociclib resistance in breast cancer by regulating MITF nuclear translocation
Cyclin-dependent kinases 4 and 6 (CDK4/6) are essential drivers of the cell cycle and are also critical for the initiation and progression of diverse malignancies. Pharmacological inhibitors targeting CDK4/6 have demonstrated significant activity against various tumor types such as breast cancer. Ho...
ORGANISM(S): Homo sapiens (Human) 
2024-05-30 | PXD042838 | Pride
Mitf Palbociclib O-glcnac 
UnknownHigh-resolution imaging reveals indirect coordination of opposite motors and a role for LIS1 in high-load axonal transport
Not available
S-JCBD-201104076 | bioimages
Proteomics,MultiomicsAPOBEC3A is an Oral Cancer Prognostic Biomarker in Taiwanese Carriers of an APOBEC Deletion Polymorphism
Chen T-W, Lee C-C, Liu H, Wu C-S, Pickering CR, Huang P-J, et al., Nature Communications 8, Article number: 465 (2017) doi:10.1038/s41467-017-00493-9

Oral squamous cell carcinoma is a prominent cancer worldwide, p...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-08-28 | MSV000084250 | MassIVE
GenomicsMapping Genes for Mammographic Density

We recruited 1,521 women from the Old Order Amish (OOA) population of Lancaster County, Pennsylvania, with the primary goal of identifying genetic factors that influence mammographic density. All women were between the ages of 40 and 88 years, with a mean of 54 years. Additional study design deta...

phs000604.v1.p1 | EGA
ProteomicsMultiomic analysis of PI3K in Atrial Myopathy
Here, we undertook comprehensive physiological and molecular analyses in cardiac-specific transgenic mice with increased or decreased PI3K to assess the dose response impact of directly regulating PI3K. Elevated PI3K was associated with a dose-dependent increase in heart size, and preserved/enhanced...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
MSV000092855 | MassIVE
ProteomicsmARC1 knockdown protects liver from diet-induced NASH in mouse
Human genetic studies have identified several MARC1 variants as protective against non-alcoholic fatty liver diseases (NAFLD). The MARC1 variants are associated with reduced lipid profiles, liver enzymes, and liver-related mortality. However, the role of mitochondrial amidoxime reducing component 1 ...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-04-28 | MSV000091820 | MassIVE
MetabolomicsGNPS - Epigenetic Control of Drought Acclimation in Sorghum (EPICON)
Two cultivars of sorghum were examined from a study performed at the Kearney Research Station in California; 1) a pre-flowering drought tolerant, post-flowering drought susceptible cultivar RTx430 and 2) a pre-flowering drought susceptible, post-flowering drought-tolerant cultivar BTx642. These dat...
ORGANISM(S): Sorghum Bicolor (ncbitaxon:4558) 
2017-10-23 | MSV000081639 | GNPS
Proteomics,MultiomicsPlasma Proteome Profiling Reveals the Effects of Weight Loss on the Apolipoprotein Family and Systemic Inflammation Status
Sustained weight loss is the preferred intervention in a wide range of metabolic conditions, but the effects on an individual´s health state remain ill-defined and controversial. Here, we investigate the plasma proteomes of a cohort of 43 obese individuals that had undergone eight weeks of weight lo...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-02 | MSV000080596 | MassIVE
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