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TranscriptomicsGenes expression profiles of postmenopausal osteoporosis with kidney Yin deficiency
Investigate genes expression profiles of postmenopausal osteoporosis with kidney Yin deficiency in peripheral blood By TCM syndrome, 10 patients with postmenopausal osteoporosis were divided into three groups: kidney Yin deficiency (n=4), kidney Yang deficiency (n=3), non-kidney deficiency (n=3), a...
ORGANISM(S): Homo sapiens 
2014-03-23 | E-GEOD-56116 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of Liuwei Dihuang Pill treatment postmenopausal osteoporosis with kidney Yin deficiency
Investigate gene expression profiles of Liuwei Dihuang Pill treatment postmenopausal osteoporosis with kidney Yin deficiency in peripheral blood Liuwei Dihuang Pill (LDP), a classic Chinese medicinal formula, has been used to treat PMO with kidney YIN deficiency for three months. Whole human genome ...
ORGANISM(S): Homo sapiens 
2014-05-06 | E-GEOD-57273 | biostudies-arrayexpress
TranscriptomicsBrown Adipose YY1 Deficiency Activates Expression of Secreted Proteins Linked to Energy Expenditure and Prevents Diet-Induced Obesity [IWAT]
Analysis of subcutaneous adipose tissue (IWAT) from Yin Yang 1 brown fat specific knockout mice fed a high fat diet for 2 weeks. The goal was to identify a gene signature of IWAT browning in YY1 mutant mice. Control mice YY1flox/flox versus YY1flox/flox; Ucp1Cre were fed a high fat diet for 2 weeks
ORGANISM(S): Mus musculus 
2015-11-10 | E-GEOD-68382 | biostudies-arrayexpress
TranscriptomicsBrown Adipose YY1 Deficiency Activates Expression of Secreted Proteins Linked to Energy Expenditure and Prevents Diet-Induced Obesity [BAT]
Analysis of brown adipose tissue from Yin Yang 1 (YY1) brown fat specific knockout mice fed a high fat diet for 3 months. YY1 deficiency in brown adipose tissue leads to strong thermogenic deficiency. The goal was to identify the genes controlled by YY1 responsible of brown fat defective function. C...
ORGANISM(S): Mus musculus 
2015-11-10 | E-GEOD-68429 | biostudies-arrayexpress
TranscriptomicsExpression data from mouse skeletal muscle
We generated skeletal muscle-specific knockout mice lacking the transcription factor Yin Yang 1 (YY1) and analyzed expression patterns in the skeletal muscle these mice. We used microarrays to detail the global programme of gene expression regulated by YY1. Wild type or knockout mice at 6 months wer...
ORGANISM(S): Mus musculus 
2012-06-29 | E-GEOD-39009 | biostudies-arrayexpress
TranscriptomicsBrown fat-specific YY1 deficiency effect on subcutaneous white adipose tissue
Analysis of visceral white adipose tissue (EWAT) from Yin Yang 1 adipose-specific knockout mice exposed to cold (4ºC) for 4 days. Control mice YY1flox/flox versus YY1flox/flox; Adiponectin Cre were cold exposed for 4 days.
ORGANISM(S): Mus musculus 
2015-11-10 | E-GEOD-70562 | biostudies-arrayexpress
GenomicsYy1 activity in mouse embryonic stem cells
This SuperSeries is composed of the following subset Series: GSE31784: Expression changes in Yy1 knock down mouse embryonic stem cells GSE31785: Yy1 occupancy of mouse ES cell genome Refer to individual Series
ORGANISM(S): Mus musculus 
2012-01-04 | E-GEOD-31786 | biostudies-arrayexpress
ProteomicsRegulation of the Endocytosis and Prion Chaperoning Machineries by Yeast E3 Ubiquitin Ligase Rsp5 as Revealed by Orthogonal Ubiquitin Transfer
Attachment of the ubiquitin (UB) peptide to proteins via the E1-E2-E3 enzymatic machinery regulates diverse biological pathways, yet identification of the substrates of E3 UB ligases remains a challenge. We overcame this challenge by constructing an “orthogonal UB transfer (OUT) cascade with yeast E...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-10-13 | PXD023688 | Pride
Ubiquitin Lc-ms/ms 
TranscriptomicsExpression changes in Yy1 knock down mouse embryonic stem cells
We have determined the global gene expression upon loss of function of the Yy1 transcription factor in mouse embryonic stem cells Total RNA was extracted from ES cells transiently transfected with yy1-specific or scrampled-control siRNA oligos 48 hr post-transfection.
ORGANISM(S): Mus musculus 
2012-01-04 | E-GEOD-31784 | biostudies-arrayexpress
GenomicsYy1 occupancy of mouse ES cell genome
These data include the genome wide location analyses of Yy1 by bioChIPs of Fbio-Yy1. Streptavidin precipitation of formaldehyde cross-linked chromatin prepared from Fbio-Yy1 and control expressing mouse ES cells
ORGANISM(S): Mus musculus 
2012-01-04 | E-GEOD-31785 | biostudies-arrayexpress
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