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UnknownSingle nucleotide polymorphisms of nucleotide excision repair and homologous recombination repair pathways and their role in the risk of osteosarcoma.
Not available
S-EPMC4476324 | biostudies-literature
UnknownEconomic evaluation of short message service intervention for HIV prevention among men who have sex with men in China: a modelling study.
Not available
S-EPMC11662610 | biostudies-literature
GenomicsGenomic Profiling of HMGN1 Reveals an Association with Chromatin at Regulatory Regions
High mobility group (HMG) proteins interact with other architectural proteins to regulate chromatin structure. We performed genome-wide mapping experiments to examine the distribution of HMGN1 across the human genome. We discovered that HMGN1 proteins are enriched at regulatory regions such as DNas...
ORGANISM(S): Homo sapiens 
2010-11-30 | E-GEOD-25674 | biostudies-arrayexpress
GenomicsThe Mediator MED23 plays opposing roles in directing smooth muscle cell and adipocyte differentiation
The Mediator complex functions as a control center orchestrating diverse signalings, gene activities, and biological processes. However, how Mediator subunits determine distinct cell fates remains to be fully elucidated. Here, we show that Mediator MED23 controls the cell fate preference that direct...
ORGANISM(S): Mus musculus 
2012-12-20 | E-GEOD-40369 | biostudies-arrayexpress
UnknownDevelopment and validation of a risk prediction model for diabetic kidney disease in patients with diabetic retinopathy.
Not available
S-EPMC12086070 | biostudies-literature
UnknownIdentification of key genes and pathways in adrenocortical carcinoma: evidence from bioinformatic analysis.
Not available
S-EPMC10694291 | biostudies-literature
TranscriptomicsMediator Complex Regulates Alternative mRNA Processing via the Med23 Subunit
Mediator complex is an integrative hub for transcriptional regulation. Here we show that Mediator regulates alternative mRNA processing via its Med23 subunit. Combining tandem affinity purification and mass spectrometry, we identified a number of mRNA processing factors that bind to a soluble recomb...
ORGANISM(S): Homo sapiens 
2012-02-24 | E-GEOD-33771 | biostudies-arrayexpress
UnknownGout drives metabolic dysfunction-associated steatotic liver disease through gut microbiota and inflammatory mediators.
Not available
S-EPMC11920238 | biostudies-literature
GenomicsThe Mediator complex subunit MED23 couples H2B mono-ubiquitination to transcriptional control and cell fate determination
The Mediator complex orchestrates multiple transcription factors with the Pol II apparatus for precise transcriptional control. However, its interplay with the surrounding chromatin remains poorly understood. Here, we analyze differential histone modifications between WT and MED23-/- (KO) cells and ...
ORGANISM(S): Mus musculus 
2015-09-16 | E-GEOD-59518 | biostudies-arrayexpress
GenomicsMediator Complex Regulates Alternative mRNA Processing via the Med23 Subunit
Mediator complex is an integrative hub for transcriptional regulation. Here we show that Mediator regulates alternative mRNA processing via its Med23 subunit. Combining tandem affinity purification and mass spectrometry, we identified a number of mRNA processing factors that bind to a soluble recomb...
ORGANISM(S): Homo sapiens 
2012-02-24 | E-GEOD-33887 | biostudies-arrayexpress
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