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MetabolomicsCombined analysis of cecal microbiota and metabolomics reveals the intervention mechanism of Dayuan Yin in acute lung injury

The ancient Chinese medicinal formula, Dayuan Yin (DYY), has a long history of use in treating respiratory ailments and shown to be effective in treating acute infectious diseases. This study aims to explore how DYY may impact intestinal flora and metabolites induced by acute lung injury (ALI). A...

2024-09-20 | MTBLS10741 | MetaboLights
ProteomicsRegulation of the Endocytosis and Prion Chaperoning Machineries by Yeast E3 Ubiquitin Ligase Rsp5 as Revealed by Orthogonal Ubiquitin Transfer
Attachment of the ubiquitin (UB) peptide to proteins via the E1-E2-E3 enzymatic machinery regulates diverse biological pathways, yet identification of the substrates of E3 UB ligases remains a challenge. We overcame this challenge by constructing an “orthogonal UB transfer (OUT) cascade with yeast E...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-10-13 | PXD023688 | Pride
Ubiquitin Lc-ms/ms 
TranscriptomicsRole of the extracytoplasmic-function sigma Factor sigmaH in Mycobacterium tuberculosis global gene expression
Like other bacterial species, Mycobacterium tuberculosis has multiple sigma (s) factors encoded in its genome. In previously published work, we and others have shown that mutations in some of these transcriptional activators render M. tuberculosis sensitive to various environmental stresses and, in ...
ORGANISM(S): Mycobacterium tuberculosis 
2007-08-03 | E-GEOD-8689 | biostudies-arrayexpress
TranscriptomicsAspergillus nidulans: Control (0 h starvation) vs. induction of starvation (12 h and 24 h) for WT, delta xprG and delta atmA
Transcriptional profiling of A. nidulans comparing starvation for 0 (reference), 12 and 24 h. The main objective was to identify genes specifically regulated during starvation by atmA and xprG. The results of the experiment were further validated by real-time PCR. Experimental procedure: Three A. ni...
ORGANISM(S): Emericella nidulans 
2012-12-07 | E-GEOD-42732 | biostudies-arrayexpress
TranscriptomicsGenes expression profiles of postmenopausal osteoporosis with kidney Yin deficiency
Investigate genes expression profiles of postmenopausal osteoporosis with kidney Yin deficiency in peripheral blood By TCM syndrome, 10 patients with postmenopausal osteoporosis were divided into three groups: kidney Yin deficiency (n=4), kidney Yang deficiency (n=3), non-kidney deficiency (n=3), a...
ORGANISM(S): Homo sapiens 
2014-03-23 | E-GEOD-56116 | biostudies-arrayexpress
TranscriptomicsBrown Adipose YY1 Deficiency Activates Expression of Secreted Proteins Linked to Energy Expenditure and Prevents Diet-Induced Obesity [IWAT]
Analysis of subcutaneous adipose tissue (IWAT) from Yin Yang 1 brown fat specific knockout mice fed a high fat diet for 2 weeks. The goal was to identify a gene signature of IWAT browning in YY1 mutant mice. Control mice YY1flox/flox versus YY1flox/flox; Ucp1Cre were fed a high fat diet for 2 weeks
ORGANISM(S): Mus musculus 
2015-11-10 | E-GEOD-68382 | biostudies-arrayexpress
TranscriptomicsBrown Adipose YY1 Deficiency Activates Expression of Secreted Proteins Linked to Energy Expenditure and Prevents Diet-Induced Obesity [BAT]
Analysis of brown adipose tissue from Yin Yang 1 (YY1) brown fat specific knockout mice fed a high fat diet for 3 months. YY1 deficiency in brown adipose tissue leads to strong thermogenic deficiency. The goal was to identify the genes controlled by YY1 responsible of brown fat defective function. C...
ORGANISM(S): Mus musculus 
2015-11-10 | E-GEOD-68429 | biostudies-arrayexpress
TranscriptomicsExpression data from mouse skeletal muscle
We generated skeletal muscle-specific knockout mice lacking the transcription factor Yin Yang 1 (YY1) and analyzed expression patterns in the skeletal muscle these mice. We used microarrays to detail the global programme of gene expression regulated by YY1. Wild type or knockout mice at 6 months wer...
ORGANISM(S): Mus musculus 
2012-06-29 | E-GEOD-39009 | biostudies-arrayexpress
TranscriptomicsComparison of transcriptomes of mouse cumulus cells collected from mice before and after 6-h of hCG priming.
We sought to identify genes that are regulated by the ovulatory signals in mouse cumulus cells. We compared the transcriptomes between cumulus cells colected from mice before (hCG-0h) and after 6 h (hCG-6h) of hCG injection. 3 individual cumulus cell samples of hCG-0h and hCG-6h were collected and s...
ORGANISM(S): Mus musculus 
2016-08-01 | E-GEOD-80255 | biostudies-arrayexpress
UnknownChildhood trauma and cognitive deficits in patients with schizophrenia: mediation by orbitofrontal cortex H-shaped sulci volume.
Not available
S-EPMC9177195 | biostudies-literature
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