Sort   by:  
 Page size 
TranscriptomicsLactic acidosis triggers starvation response with distinct metabolic profiles
[1] Lactic acidosis time course: MCF7 cells were exposed to lactic acidosis for different length of time. We used microarrays to examine the genomic programs of cells incubated under lactic acidosis for different length of time [2] Metabolic profiling: MCF7 cells were exposed to control condition, ...
ORGANISM(S): Homo sapiens 
2010-09-27 | E-GEOD-19123 | biostudies-arrayexpress
MetabolomicsChitin utilization by marine picocyanobacteria and the evolution of a planktonic lifestyle.
Marine picocyanobacteria Prochlorococcus and Synechococcus, the most abundant photosynthetic cells in the oceans, are generally thought to have a primarily single-celled and free-living lifestyle. However, while studying the ability of picocyanobacteria to supplement photosynthetic car...
2024-02-21 | MTBLS5229 | MetaboLights
TranscriptomicsTranscription profiling of S. cerevisiae haploid Sigma1278b strains with msa1 or msa2 or tec1 deletions
We determined and classified Msa1-, Msa2- and Tec1-regulated genes in haploid strains of the Sigma1278b genetic background under vegetative growth conditions. For this purpose, we measured transcriptional profiles of five different haploid MATa yeast strains of the following relevant genotypes: (Jvd...
ORGANISM(S): Saccharomyces cerevisiae 
2013-10-25 | E-MEXP-3619 | biostudies-arrayexpress
TranscriptomicsMolecular mechanisms of cigarette smoke-induced lung emphysema
Chronic obstructive pulmonary disease (COPD) is a complex pulmonary disorder primarily induced by cigarette smoking, and characterized by persistent airflow limitation. The mouse represents an important model for studying COPD pathologies such as lung emphysema. In this respect, a number of mechanis...
ORGANISM(S): Mus musculus 
2014-11-28 | E-MTAB-2756 | biostudies-arrayexpress
TranscriptomicsChIPseq of PPARbeta/delta in MDA-MB-231luc cells
Chromatin-immunoprecipitated with antiPPARD and antiRXR antibodies was performed in MDA-MB-231luc1 cells.
ORGANISM(S): Homo_sapiens 
2013-02-26 | E-MTAB-1097 | biostudies-arrayexpress
TranscriptomicsEstrogen-mediated Epigenetic Repression of Large Chromosomal Regions through DNA Looping
The current concept of epigenetic repression is based on one repressor unit corresponding to one silent gene. This notion, however, cannot adequately explain concurrent silencing of multiple loci observed in large chromosome regions. The long-range epigenetic silencing (LRES) can be a frequent occur...
ORGANISM(S): Homo sapiens 
2010-04-29 | E-GEOD-21068 | biostudies-arrayexpress
TranscriptomicsCaM Kinase II mediates maladaptive post-infarct remodeling but not acute myocardial ischemia/reperfusion injury
Calcium/calmodulin-dependent protein kinase II (CaMKII) was suggested to mediate ischemic myocardial injury and adverse cardiac remodeling. However, the specific functions of the CaMKII isoforms and splice variants in ischemia/reperfusion (I/R) injury have not been investigated yet. Thus, we studied...
ORGANISM(S): Mus musculus 
2014-09-08 | E-GEOD-58486 | biostudies-arrayexpress
UnknownOncogenic PIK3CA corrupts growth factor signaling specificity
Not available
S-SCDT-10_1038-S44320-024-00078-X | biostudies-other
ProteomicsPosternak_PROTACagainstBRAFV600E_P124_Lumos
The files are associated with a manuscript submitted for publication by Ganna Posternak et al. The main goal of this paper was functionally characterize the mechanism of action of a PROTAC designed to target BRAFV600E.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-11-07 | MSV000084551 | MassIVE
ProteomicsPosternak_PROTACdegradation_P124_Lumos
The files are associated with a manuscript submitted for publication by Ganna Posternak et al. The main goal of this paper was functionally characterize the mechanism of action of a PROTAC designed to target BRAFV600E. This dataset provides a proteome-wide view of protein degradation after treatment...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-04-10 | MSV000085271 | MassIVE
Sort   by:  
 Page size