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TranscriptomicsTranscriptome analysis of a Staphylococcus aureus mutant defective in the transcription termination factor Rho.
This analysis is part of the study Whole-transcriptome analysis of Staphylococcus aureus under laboratory and infection-mimicking conditions (Mäder, Nicolas et al., to be submitted) where the S. aureus HG001 transcriptome was analyzed under more than 40 different biological conditions. The data rev...
ORGANISM(S): Staphylococcus aureus 
2016-03-08 | E-GEOD-70041 | biostudies-arrayexpress
TranscriptomicsVALIDATION STUDY TO VERIFY DIAGNOSTIC MARKERS FOR LUNG CANCER IN ENDOBRONCHIAL LINING FLUID
We investigated whether biomarker analysis in endobronchial epithelial lining fluid (ELF) collected by bronchoscopic microsampling may be useful for a definitive preoperative diagnosis. Therefore we compared ELF samples close to nodule and from the contralateral site from patients with malignant or ...
ORGANISM(S): Homo sapiens 
2011-12-31 | E-GEOD-27553 | biostudies-arrayexpress
TranscriptomicsGene expression analysis in control and HIF-2 alpha deficient murine lung endothelial cells under hypoxia
Journal : Blood. 2009 Jul 9;114(2):469-77. Epub 2009 May 13. Title : Endothelial deletion of hypoxia-inducible factor-2alpha (HIF-2alpha) alters vascular function and tumor angiogenesis. Authors : Skuli N, Liu L, Runge A, Wang T, Yuan L, Patel S, Iruela-Arispe L, Simon MC, Keith B. Abstract : Hyp...
ORGANISM(S): Mus musculus 
2009-07-15 | E-GEOD-16067 | biostudies-arrayexpress
Transcriptomicskeyzer_Lonlay
Transcriptom profiling performed on myotubes derived from 3 patients carrying two recessively-inherited mutations in LPIN1 gene and 3 age and sex matched controls with or without TNF-alpha plus IL-1-beta stimulation for 24h.
ORGANISM(S): Homo sapiens 
2013-10-17 | E-MEXP-3761 | biostudies-arrayexpress
TranscriptomicsNoise in rpoS expression determines cellular permissiveness for horizontal transfer of an Integrative and Conjugative Element
To support our molecular hypothesis of the effect of rpoS and inrR genes over the activation of the ICEclc genome in Pseudomonas knackmussii B13, we have employed Agilent DNA custom microarray in the 8X15K format. ICEclc-specific gene expression in Pseudomonas knackmussii strain B13 was measured aft...
ORGANISM(S): Pseudomonas knackmussii 
2012-09-01 | E-GEOD-35501 | biostudies-arrayexpress
TranscriptomicsThe role of Ternary Complex factors in T-cell Positive Selection
Removal of the transcription factor SAP1a member of the Ternary Complex Factor (TCF) group of transcription factors which in conjunction with Serum Response Factor (SRF) has been shown to have a profound effect on positive selection in the thymus. When another TCF Elk1 is knocked out in mice there i...
ORGANISM(S): Mus musculus 
2010-06-08 | E-GEOD-21546 | biostudies-arrayexpress
TranscriptomicsThe small RNA PhrS stimulates synthesis of the Pseudomonas aeruginosa quinolone signal
Quorum sensing, a cell-to-cell communication system based on small signal molecules, is employed by the human pathogen Pseudomonas aeruginosa to regulate virulence and biofilm development. Moreover, regulation by small trans-encoded RNAs has become a focal issue in virulence gene expression of bacte...
ORGANISM(S): Pseudomonas aeruginosa 
2011-06-27 | E-GEOD-25595 | biostudies-arrayexpress
TranscriptomicsTranscriptome profiling of Drosophila intestinal cells
Purpose: We isolated Drosophila midgut cells : Delta+ intestinal stem cells (ISCs), Su(H)+enteroblasts (EBs), Esg+ cells (ISC+EB), Myo1A+Enterocytes (ECs), Pros+Enteroendocrine cells (EEs) and How+Visceral muscle cells (VM) from whole midguts to identify stem cell specific genes and study cell type ...
ORGANISM(S): Drosophila melanogaster 
2015-05-23 | E-GEOD-61361 | biostudies-arrayexpress
TranscriptomicsNovel targets of the CbrAB/Crc carbon catabolite control system revealed by transcript abundance in Pseudomonas aeruginosa [LB]
The opportunistic human pathogen Pseudomonas aeruginosa can utilize several carbon and nitrogen compounds as energy sources, which allows the bacterium to grow on a variety of different environments. Nevertheless, the uptake and utilization of these compounds is organized in a hierarchical manner, w...
ORGANISM(S): Pseudomonas aeruginosa 
2012-03-31 | E-GEOD-33244 | biostudies-arrayexpress
GenomicsRRBS of human fetal testis treated to a mixture of DEHP/BPA
Fetal human fetal testes (8-11 weeks post-fertilization [WPF]) were cut into small pieces (~1 mm3 ) and 4-6 pieces/testis (depending of the age or size of the gonad) were insert into the muscle of the left back of two twin female mice. One week after surgery, one mouse was exposed by drinking water ...
ORGANISM(S): Homo sapiens 
2026-01-01 | E-MTAB-13840 | biostudies-arrayexpress
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