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Transcriptome sequencing was performed on 214 patients with myelodysplasia in this study. RNA was obtained from bone marrow CD34+ cells (n=100) and/or bone marrow mononuclear cells (n=165). Transcriptome sequencing was performed for both cell fractions in 51 patients. A total of 211 patients were ge...
Transcriptome sequencing was performed on 214 patients with myelodysplasia in this study. RNA was obtained from bone marrow CD34+ cells (n=100) and/or bone marrow mononuclear cells (n=165). Transcriptome sequencing was performed for both cell fractions in 51 patients. We also studied bone marrow CD3...
To characterize the molecular features of p53 signaling pathway, we generated the gene-expression profiles of p53-introduced U373MG cells by genome-wide cDNA microarrays Keywords: time course U373MG cells were infected with 20 MOI of Ad-p53 or Ad-LacZ. mRNA from infected cells were collected at 0...
ORGANISM(S): Homo sapiens 
DNA methylation profiling of 106 ccRCC tumors by the Illumina Infinium 450k Human Methylation Beadchip
ORGANISM(S): Homo sapiens 
Copy number analysis of Affymetrix 250K SNP arrays was performed for 240 clear cell RCC samples. There are also 234 samples from adjacent normal kidney or peripheral blood, which were used as references for copy number inference.
ORGANISM(S): Homo sapiens 
Gene expression in clear cell RCC was measured for 101 samples
ORGANISM(S): Homo sapiens 
Infinium 450K in Rhabdomyosarcoma
Whole-exome sequencing in 16 RMS cases Whole-transcriptome sequencing in 8 RMS cases
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in childhood. To unravel the genetic/epigenetic basis of RMS, we studied 60 RMS cases using whole exome/transcriptome sequencing, copy number (CN) profiling, and DNA methylome analysis. Based on DNA methylation patterns, RMS was clustered...
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