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TranscriptomicsArray CGH data of A. oryzae strains bearing targeted tandem chromosomal duplications
We here describe the first successful construction of a targeted tandem duplication of a large chromosomal segment in Aspergillus oryzae. The targeted tandem chromosomal duplication was achieved by using strains that had 5M-bM-^@M-^YM-NM-^TpyrG upstream of the region targeted for tandem chromosomal ...
ORGANISM(S): Aspergillus oryzae RIB40 
2014-06-30 | E-GEOD-57246 | biostudies-arrayexpress
TranscriptomicsThe RANK/RANKL axis controls vascular dynamics in the bone marrow
Receptor activator of nuclear factor kappa B ligand (RANKL) is an essential cytokine that induces osteoclastic differentiation by monocyte-macrophage lineage precursors. Here, we showed that in addition to its conventional action, RANKL controls vascular permeability in the bone marrow, where it fac...
ORGANISM(S): Mus musculus 
2025-10-23 | E-MTAB-15929 | biostudies-arrayexpress
TranscriptomicsIdentification of EP4 as a Potential Target for the Treatment of Castration-Resistant Prostate Cancer Using a Novel Xenograft Model
More effective therapeutic approaches for castration-resistant prostate cancer (CRPC) are urgently needed, thus reinforcing the need to understand how prostate tumors progress to castration resistance. We have established a novel mouse xenograft model of prostate cancer, KUCaP-2, which expresses the...
ORGANISM(S): Homo sapiens 
2010-06-08 | E-GEOD-21887 | biostudies-arrayexpress
TranscriptomicsMicroRNA expression profiling predicts clinical outcome of chronic hepatitis C by interferon administration
We attempt to catalog the microRNA (miRNA) expression profile according to the response of combination therapy in order to predict the outcome of drug-response before administration and clarify the relationship between aberrant expression of miRNAs and chronic liver disease. We quantified expression...
ORGANISM(S): Homo sapiens 
2010-12-30 | E-GEOD-16922 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of serous ovarian cancer samples
To elucidate the mechanisms of rapid progression of serous ovarian cancer, gene expression profiles from forty-three ovarian cancer tissues comprising eight early stage and thirty-five advanced stage tissues were performed using oligonucleotide microarrays of 18,716 genes. By non-negative matrix fac...
ORGANISM(S): Homo sapiens 
2009-07-19 | E-GEOD-12470 | biostudies-arrayexpress
ProteomicsProtein expression in heated rat lens using shotgun proteomics
Previous studies have reported that a strong correlation between the estimated cumulative thermal exposure in the crystalline lens and the incidence of nuclear cataracts; however, the precise relationship between temperature and cataracts remains to be fully elucidated. In the present study, the sho...
ORGANISM(S): Rattus 
2024-09-22 | PXD056067 | JPOST Repository
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