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TranscriptomicsGene expression of murine B cells activated via TLR4 or TLR4 + CD40: Group1 naM-CM-/ve B cells, Group2 LPS activated B cells 24h, Group3 LPS + anti-CD40 activated B cells 24h, Group4 LPS activated B cells 72h, and Group5 LPS + anti-CD40 activated B cells 72h.
Murine B cells can be activated via the surface receptors TLR4 and CD40. For a global assessment of differences in gene expression between these two different modes of B cell activation a genome wide transcriptome analysis was performed. In order to dissect different gene expression profiles of B ce...
ORGANISM(S): Mus musculus 
2014-02-24 | E-GEOD-35998 | biostudies-arrayexpress
UnknownCooling field and temperature dependent exchange bias in spin glass/ferromagnet bilayers.
Not available
S-EPMC4562234 | biostudies-literature
TranscriptomicsPorcine spleen_Haemophilus Parasuis infected_7days
Haemophilus parasuis(HPS) is a prominent swine pathogen that causes GlM-CM-$sser's disease characterized by fibrinous polyserositis, meningitis and arthritis; however, the molecular mechanisms underlying disease pathogenesis remains poorly understood, particularly the host counteraction to HPS invas...
ORGANISM(S): Sus scrofa 
2009-03-26 | E-GEOD-11787 | biostudies-arrayexpress
TranscriptomicsTesticular germ cell tumor susceptibility genes from the consomic 129.MOLF-Chr19 mouse strain
Chromosome substitution strains (CSS or consomic strains) are useful for mapping phenotypes to chromosomes. However, huge efforts are needed to identify the gene(s) responsible for the phenotype in the complex context of the chromosome. Here, we report the identification of candidate disease genes...
ORGANISM(S): Mus musculus 
2009-01-13 | E-GEOD-14354 | biostudies-arrayexpress
ProteomicsIntratracheal lipopolysaccharide (LPS)-induced acute lung injury (ALI) in Mouse Serum and lung DIA Proteomics Profiling
The aim of this project was to profile the proteome of mouse-derived serum in order to identify those that showed significant quantitative different proteins among ALI mice and controls.
ORGANISM(S): Mus Musculus 
2023-01-20 | PXD039618 |
Transcriptomicsidentification of TGCT genes involved in initiation and maintenance of transformed germ cells.
Initially, we had compared gene expression differences in the embryonic gonads (E13.5) of the 129 and M19 strains by performing microarray analysis. These studies allowed us to identify downregulation of expression of the D19Bwg1357e, Zfp162 and Cox15 genes in the M19 strain. We next decided to exa...
ORGANISM(S): Mus musculus 
2009-12-30 | E-GEOD-14481 | biostudies-arrayexpress
ProteomicsMicroscopy-based functional single cell proteomic profiling of cells with abnormal DNA damage response dynamics
Tumor heterogeneity is an important source of cancer therapy resistance. Single cell proteomics has the potential to decipher protein content leading to heterogeneous cellular phenotypes. Single-Cell ProtEomics by Mass Spectrometry (SCoPE-MS) is a recently developed, promising, unbiased proteomic pr...
ORGANISM(S): Homo sapiens (Human) 
2022-07-07 | PXD034370 | Pride
Single-cell proteomics 
GenomicsCell type-specific binding patterns reveal that TCF7L2 can be tethered to the genome by association with GATA3
The TCF7L2 transcription factor is linked to a variety of human diseases, including type 2 diabetes and cancer. One mechanism by which TCF7L2 could influence expression of genes involved in diverse diseases is by binding to distinct regulatory regions in different tissues. To test this hypothesis, ...
ORGANISM(S): Homo sapiens 
2012-06-05 | E-GEOD-38447 | biostudies-arrayexpress
UnknownSensitizing acute myeloid leukemia cells to induced differentiation by inhibiting the RIP1/RIP3 pathway.
Not available
S-EPMC5457287 | biostudies-literature
UnknownAmbient Documentation Technology in Clinician Experience of Documentation Burden and Burnout.
Not available
S-EPMC12371510 | biostudies-literature
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