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ProteomicsOuter Membrane Vesicles Secreted by Bacteroides fragilis Inhibit CFTR Chloride Secretion by Human Colon Organoids
The goals of this study were to develop a model to study host pathogen interactions in primary human colon organoids and to test the hypothesis that Bacteroides fragilis toxin (BFT-2) secreted in outer membrane vesicles (OMVs) modulates mucosal immunity and CFTR Cl- secretion. Since Bacteroides spec...
ORGANISM(S): Bacteroides fragilis 
2026-05-21 | PXD073462 | Pride
Transepithelial resistance Cftr Bacteroides fragilis Colon organoids Outer membrane vesicles 
ProteomicsExtracellular Particles Derived from Mesenchymal Stromal Cells Reduce Pseudomonas aeruginosa Lung Infection and Inflammation in Mice
The World Health Organization and the U.S. Centers for Disease Control and Prevention have reported that antibiotic resistant infections with Pseudomonas aeruginosa present a significant health risk world-wide. In the genetic disease Cystic Fibrosis (CF), chronic antibiotic resistant Pseudomonas lun...
ORGANISM(S): Homo sapiens (Human) 
2026-02-23 | PXD070855 | Pride
Mesenchymal stromal cells Extracellular particles Lung disease Antibiotic resistance Inflammation Pseudomonas aeruginosa Cystic fibrosis 
UnknownDecreased memory B cells frequencies in COVID-19 Delta variant vaccine breakthrough infection
Not available
S-SCDT-EMM-2021-15227 | biostudies-other
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