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TranscriptomicsTranscription profiling of rat hippocampus from young and aged rats with age-related spatial learning impairments
The aim of this study was to investigate whether the differences in memory decline associated with aging are a result of differences in gene expression. We first categorized age-unimpaired and age-impaired rats based on their performance in the Morris Water Maze and then isolated messenger RNA from...
ORGANISM(S): Rattus norvegicus 
2007-11-06 | E-GEOD-3531 | biostudies-arrayexpress
UnknownConditions of gestation, childbirth and childhood associated with C-peptide in young adults in the 1982 Birth Cohort in Pelotas-RS; Brazil.
Not available
S-EPMC5504841 | biostudies-literature
UnknownImpact of the COVID-19 pandemic on maternal mental health, early childhood development, and parental practices: a global scoping review.
Not available
S-EPMC9950022 | biostudies-literature
MetabolomicsSarcopenic metabolomic profile reflected a sarcopenic phenotype associated with amino acid and essential fatty acid changes

INTRODUCTION: Although sarcopenia greatly affects health and quality of life in older people, its pathophysiological causes are not fully elucidated. To face this challenge, omics technologies can be used. The metabolome gives a vision of the interaction between the genome and t...

2021-09-29 | MTBLS2679 | MetaboLights
TranscriptomicsThe let-7-Imp axis regulates aging of the Drosophila testis stem cell niche.
Adult stem cells support tissue homeostasis and repair throughout the life of an individual. However, numerous intrinsic and extrinsic changes occur with age that result in altered stem cell behavior and reduced tissue maintenance and regeneration. In the Drosophila testis, stem cells surround and c...
ORGANISM(S): Drosophila melanogaster 
2012-05-31 | E-GEOD-37041 | biostudies-arrayexpress
TranscriptomicsHost Responses to Sepsis Vary in Different Low-Lethality Murine Models
The CS and CLP murine models of intra-abdominal sepsis have unique transcriptomic respones 2 hrs, 1 and 3 days after sepsis We used mouse microarrays to detail the molecular profile of the events that occur following infection in two different sepsis models Infection protocol: Used the Cecal Ligatio...
ORGANISM(S): Mus musculus 
2014-02-21 | E-GEOD-55238 | biostudies-arrayexpress
GenomicsNeuroblastoma Genome-Wide Association Study (NBL-GWAS)

Neuroblastoma is a malignancy of the developing sympathetic nervous system that most commonly affects young children and is often lethal. The etiology of this embryonal cancer is not known.

We have performed a whole genome scan for association of neuroblastoma with SNP genotypes an...

phs000124.v2.p1 | EGA
TranscriptomicsBisphenol A Exposure and Multiple Sclerosis Risk
Bisphenol A Exposure and Multiple Sclerosis Risk Comparison of vehicle-treated vs. BPA-treated mouse testes tissue. Each comparison in technical and biological duplicate (Done twice: total 4 replicates)
ORGANISM(S): Mus musculus 
2013-10-22 | E-GEOD-45917 | biostudies-arrayexpress
UnknownAge-Related Electrocardiographic Characteristics of Male Junior Soccer Athletes.
Not available
S-EPMC8850359 | biostudies-literature
TranscriptomicsAged Mice are Unable to Mount an Effective Myeloid Response to Sepsis
Old C57BL/6 mice cannot mount an effective innate immune response We used mouse microarrays to detail the molecular profile of the events that occur following infection
ORGANISM(S): Mus musculus 
2014-02-04 | E-GEOD-51925 | biostudies-arrayexpress
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