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MetabolomicsFaecal microbiota transplant from aged donor mice affects spatial learning and memory via modulating hippocampal synaptic plasticity- and neurotransmission-related proteins in young recipients

BACKGROUND: The gut-brain axis and the intestinal microbiota are emerging as key players in health and disease. Shifts in intestinal microbiota composition affect a variety of systems, however, evidence of their direct impact on cognitive functions is still lacking. We tested whe...

2021-12-17 | MTBLS1437 | MetaboLights
TranscriptomicsPromoter proximal pausing and its regulation by c-Myc in embryonic stem cells: ChIP-chip
Recruitment of the RNA Polymerase II (Pol II) transcription initiation apparatus to promoters by specific DNA binding transcription factors is well recognized as a key regulatory step in gene expression. We describe here evidence that promoter-proximal pausing is a general feature of transcription ...
ORGANISM(S): Mus musculus 
2010-04-02 | E-GEOD-20529 | biostudies-arrayexpress
TranscriptomicsExpression data from young and adult mice after over expression of self MHC class l protein in skeletal muscle.
Over expression of MHC Class l protein in skeletal muscle causes myositis. Phenotype after expression in young mice is more severe. We performed gene expression profiling on young and adult mice after over expression of self MHC class l protein in skeletal muscle Muscle from young ( early) , adult ...
ORGANISM(S): Mus musculus 
2009-06-02 | E-GEOD-14997 | biostudies-arrayexpress
GenomicsPromoter proximal pausing and its regulation by c-Myc in embryonic stem cells: ChIP-Seq
Recruitment of the RNA Polymerase II (Pol II) transcription initiation apparatus to promoters by specific DNA binding transcription factors is well recognized as a key regulatory step in gene expression. We describe here evidence that promoter-proximal pausing is a general feature of transcription ...
ORGANISM(S): Mus musculus 
2010-04-02 | E-GEOD-20530 | biostudies-arrayexpress
UnknownInfluence of Morphometry on Echocardiographic Measurements in Cavalier King Charles Spaniels: An Inverse Probability Weighting Analysis.
Not available
S-EPMC8538534 | biostudies-literature
TranscriptomicsTranscription profiling of vastus lateralis muscle from healthy young (21-31 year old) and older (62-77 year old) men
RNA from vastus lateralis of healthy young (21-31 year old) and older (62-77 year old) men. Signal data normalized to mean intensity of 500 over all probes sets. Analysis done with Affymetrix Microarray Suite 5.0 software.
ORGANISM(S): Homo sapiens 
2007-10-30 | E-GEOD-80 | biostudies-arrayexpress
TranscriptomicsEffect of dDAVP on outer medullary gene expression in Brattleboro rats
Activation of the renal urine concentrating mechanism by vasopressin requires the coordinated regulation of multiple gene products including ion transporters, and water channels as well as regulatory proteins like protein kinases and phosphatases or enzymes involved in the energy-metabolism of the c...
ORGANISM(S): Rattus norvegicus 
2012-03-01 | E-GEOD-34225 | biostudies-arrayexpress
UnknownCirculating MiR-30b-5p is upregulated in Cavalier King Charles Spaniels affected by early myxomatous mitral valve disease.
Not available
S-EPMC9273067 | biostudies-literature
UnknownWhole-genome assembly and annotation of the acorn weevil, Curculio nanulus (Coleoptera: Curculionidae).
Not available
S-EPMC12869062 | biostudies-literature
TranscriptomicsTranscripts regulated by elevated DKF-2 (WT background)
Transcriptional profiling was used to determine why DKF-2 (protein kinase D) deficiency and surfeit caused hypersensitivity and resistance, respectively, to a bacterial pathogen (P. aeruginosa 14). The studies show that DKF-2 contributes to C. elegans innate immunity by inducing expression of >75 ge...
ORGANISM(S): Caenorhabditis elegans 
2009-01-12 | E-GEOD-12456 | biostudies-arrayexpress
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