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Recruitment of the RNA Polymerase II (Pol II) transcription initiation apparatus to promoters by specific DNA binding transcription factors is well recognized as a key regulatory step in gene expression. We describe here evidence that promoter-proximal pausing is a general feature of transcription ...
ORGANISM(S): Mus musculus 
The aim of this work was to analyze the transcriptomic response of Buchnera when the aphid host is submitted to a depletion of tyrosine and phenyalanine, two amino acids that are essential to its development. The data set is composed of 8 slides arranged in a dye swap experimental design. We compare...
ORGANISM(S): Buchnera aphidicola 
Recruitment of the RNA Polymerase II (Pol II) transcription initiation apparatus to promoters by specific DNA binding transcription factors is well recognized as a key regulatory step in gene expression. We describe here evidence that promoter-proximal pausing is a general feature of transcription ...
ORGANISM(S): Mus musculus 
The aim of this work was to analyze the transcriptomic response of Buchnera aphidicola when the aphid host is submitted to depletion in essential amino acids (EAA). This treatment was combined with an increase in sucrose concentration to influence the bacterial growth rate. In this experiment, the d...
ORGANISM(S): Buchnera aphidicola 
Triple negative breast cancer (TNBC) is a heterogeneous and clinically aggressive disease for which there is no targeted therapy. Here we report the preferential and high sensitivity of TNBCs to BET bromodomain inhibitors such as JQ1 manifested by cell cycle arrest in early G1, apoptosis, and induct...
ORGANISM(S): Homo sapiens 
Triple negative breast cancer (TNBC) is a heterogeneous and clinically aggressive disease for which there is no targeted therapy. Here we report the preferential and high sensitivity of TNBCs to BET bromodomain inhibitors such as JQ1 manifested by cell cycle arrest in early G1, apoptosis, and induct...
ORGANISM(S): Homo sapiens 
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