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MetabolomicsCroquemort elicits activation of the immune deficiency pathway in ticks
The immune deficiency (IMD) pathway directs host defense in arthropods upon bacterial infection. In Pancrustacea, peptidoglycan recognition proteins sense microbial moieties and initiate nuclear factor-κB-driven immune responses. Proteins that elicit the IMD pathway in non-insect arthropods remain e...
2023-04-27 | MTBLS686 | MetaboLights
TranscriptomicsTranscription profiling validation of an custom mouse oligo array using liver samples following treatment with the hepatotoxin phenobarbital and variable hybridization protocols
The use of custom-made focused microarrays has become a popular alternative, allowing the study of genes relevant to a specific hypothesis. To address the limitations of commercial arrays in toxicogenomics investigations, we have developed a custom mouse oligonucleotide microarray, the HC ToxArrayTM...
ORGANISM(S): Mus musculus 
2006-10-30 | E-MEXP-525 | biostudies-arrayexpress
TranscriptomicsThe NuA4 complex promotes Translesion Synthesis (TLS) - mediated DNA damage tolerance
DNA lesions can block a replication fork, leading to its collapse and gross chromosomal rearrangements. To circumvent such outcomes, DNA damage tolerance (DDT) pathways become engaged, allowing the replisome to bypass the lesion and complete S phase in the presence of unrepaired damage. Here we demo...
ORGANISM(S): Saccharomyces cerevisiae 
2015-02-21 | E-GEOD-66176 | biostudies-arrayexpress
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