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MetabolomicsTrans-tissue molecular coordination in high-intensity physical activity
High-intensity physical activity has major impacts in different parts of the body. However, the regulatory coordination between different tissues to support the high physical demands is poorly understood. Here we performed a multi-omics analysis of blood plasma, urine and saliva from a group of fire...
2025-07-03 | MTBLS1891 | MetaboLights
ProteomicsLabel-free quantitative (LFQ) proteomic analysis of redox mediated posttranslational modifications (PTM) in the cartilage from young and old osteoarthritis (OA) mice with or without the senolytic treatment
Senolytic drugs are designed to selectively clear senescent cells (SnCs) that accumulate with injury or aging. In a mouse model of osteoarthritis (OA), senolysis yields a pro-regenerative response. However, recent research studies showed that the therapeutic benefit is reduced in aged mice. Increase...
ORGANISM(S): Mus musculus (Mouse) 
2023-09-26 | PXD031782 | Pride
Mouse model of osteoarthritis (oa)  senolytic treatment  label-free quantitative (lfq) proteomic  analysis of redox ptms in the cartilage proteins 
UnknownSexual Intercourse Frequency During Pregnancy: Weekly Surveys Among 237 Young Women From A Random Population-Based Sample.
Not available
S-EPMC9529844 | biostudies-literature
UnknownRisk of Incident and Fatal Colorectal Cancer After Young-Onset Adenoma Diagnosis: A National Cohort Study.
Not available
S-EPMC10524098 | biostudies-literature
UnknownAppetite Suppression and Altered Food Preferences Coincide with Changes in Appetite-Mediating Hormones During Energy Deficit at High Altitude, But Are Not Affected by Protein Intake.
Not available
S-EPMC6014054 | biostudies-literature
TranscriptomicsRestoring Systemic GDF11 Levels Reverses Age-Related Dysfunction in Mouse Skeletal Muscle
In this study, we investigated signaling pathways in Skeletal muscle precursors that are altered with aging and age-related deficits in muscle regenerative potential. We performed fluorescence activated cell sorting (FACS) to obtain highly purified skeletal muscle satellite cells from young, middle-...
ORGANISM(S): Mus musculus 
2014-05-08 | E-GEOD-50821 | biostudies-arrayexpress
TranscriptomicsComplement Factor H deficiency results in decreased neuroretinal expression of Cd59a in aged mice.
Purpose: The complement system is closely linked to the pathogenesis of age-related macular degeneration (AMD). Several complement genes are expressed in retinal pigment epithelium (RPE), and complement proteins accumulate in drusen. Further, a common variant of complement factor H (CFH) confers inc...
ORGANISM(S): Mus musculus 
2012-10-02 | E-GEOD-38671 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Lumbricus rubellus to determine seasonal changes in gene expression
To determine the developmental and seasonal variation in transcript expression within a terrestial sentinal, the earthworm Lumbricus rubellus.
ORGANISM(S): synthetic_DNA 
2008-01-08 | E-MAXD-36 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human low gestational age newborns as predictors of bronchopleural pulmonary dysplasia
One third to one half of all infants born before the 28th wek of gestation develop BPD bronchopulmonary dysplasia. Our objective is to evaluate the feasibility of using expression profiling in umbilical cord tissue to discover molecular signatures for developmental staging and for risk of BPD. Expe...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-8586 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of earthworm Lumbrius rubellus after treatment with a sub-lethal dose of cadmium
To determine the transcriptome sub-lethal dose response profile for adult Lumbricus rubellus exposued to Cadmium.
ORGANISM(S): synthetic 
2007-12-17 | E-MAXD-34 | biostudies-arrayexpress
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