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TranscriptomicsGene profile analysis of sorted Sca1+/cKit- BMCs obtained from young and aged mice bearing tumor or not
Sca1+/cKit– hematopoietic BMCs of hosts bearing primary tumors promote the growth of distant tumors that form with a myofibroblast-rich, desmoplastic stroma. BMCs from old mice bearing primary tumors lack this ability Sca1+/cKit- BMCs were isolated from young and old mice bearing Matrigel control ...
ORGANISM(S): Mus musculus 
2016-07-21 | E-GEOD-74120 | biostudies-arrayexpress
MetabolomicsFlavonoid Biosynthesis Is Likely More Susceptible to Elevation and Tree Age Than Other Branch Pathways Involved in Phenylpropanoid Biosynthesis in Ginkgo Leaves
Ginkgo leaves are always resources for flavonoids pharmaceutical industry. However, the effect of the elevation and tree age changes on flavonoid biosynthesis have not been detailly explored in Ginkgo leaves. In addition, whether these environmental pressures have similar effects on the biosynthesis...
2020-12-14 | MTBLS962 | MetaboLights
UnknownReal-world study of children and young adults with myeloproliferative neoplasms: identifying risks and unmet needs.
Not available
S-EPMC9631631 | biostudies-literature
TranscriptomicsTranscriptome sequencing for cancer stem cell properties in MCF-7 cells with knocked down CD24
CD24 is the one of cell surface protein that anchored via glycosyl phosphatidylinositol that links to cell surface and modulates growth and differentiation signal many of cell types. A small population of cells, namely M-bM-^@M-^XCancer Stem Cells (CSCs)M-bM-^@M-^Y, charges highly aggressive and met...
ORGANISM(S): Homo sapiens 
2014-10-15 | E-GEOD-61917 | biostudies-arrayexpress
Transcriptomicssingle cell RNAseq of memory B cells in the context of rituximab-treated ITP patients
Rituximab (RTX) is widely used as a first-line therapeutic strategy in B cell-mediated autoimmune diseases. However, a large proportion of patients either do not respond to the treatment or relapse during B cell reconstitution. Primary immune thrombocytopenia (ITP) is a prototypic B cell mediated au...
ORGANISM(S): Homo sapiens 
2021-01-31 | E-MTAB-9955 | biostudies-arrayexpress
UnknownLactiplantibacillus plantarum P9 for chronic diarrhea in young adults: a large double-blind, randomized, placebo-controlled trial.
Not available
S-EPMC11315937 | biostudies-literature
TranscriptomicsTemporal patterns in the transcriptomic response of rainbow trout, Oncorhynchus mykiss, to crude oil
Time is often not characterized as a variable in ecotoxicogenomic studies. In this study, the temporal kinetics in gene expression were determined during exposure to crude oil and a subsequent recovery period. Juvenile rainbow trout, Oncorhynchus mykiss, were exposed for 96 hours to the water accom...
ORGANISM(S): Oncorhynchus mykiss 
2010-05-18 | E-GEOD-19489 | biostudies-arrayexpress
UnknownAge-specific differences in non-cardiac comorbidities among elderly patients hospitalized with heart failure: a special focus on young-old, old-old, and oldest-old.
Not available
S-EPMC6964950 | biostudies-literature
TranscriptomicsTranscription profiling of human Burkitts lymphoma cells (L3055) treated with low and high concentrations of CD154
Activated B cells reacting to small amounts of CD40 ligand (CD154) maintain homeostasis by suppressing default apoptosis. Additional outcomes, particularly differentiation, demand higher CD40 occupancy. Here we compared changes in the transcriptome of pleiotropically competent, early-passage L3055 B...
ORGANISM(S): Homo sapiens 
2007-05-31 | E-MEXP-1113 | biostudies-arrayexpress
UnknownImproving the Production of Riboflavin by Introducing a Mutant Ribulose 5-Phosphate 3-Epimerase Gene in Bacillus subtilis.
Not available
S-EPMC8359813 | biostudies-literature
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